7214630

CD33 Mouse, anti-Human, R718, Clone: WM53, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD33

Applications

Flow Cytometry

Conjugate

R718

Host Species

Mouse

Target Species

Human

Content And Storage

Refrigerate Upon Arrival

Clone

WM53

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Primary or Secondary

Primary

Description

  • The WM53 monoclonal antibody specifically recognizes CD33 which is also known as Sialic acid-binding Ig-like lectin 3 (Siglec-3) or gp67
  • CD33 is a 67 kDa type I transmembrane glycoprotein that is variably expressed on myeloid progenitors, monocytes, macrophages, dendritic cells, neutrophils, basophils, mast cells, and on some activated T cells and NK cells
  • Normal lymphocytes, platelets, erythrocytes and pluripotent hematopoietic stem cells do not express the CD33 antigen
  • This glycoprotein reportedly functions as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.

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