The price for this product is unavailable. Please request a
quote
Antigen
CD33
Applications
Flow Cytometry
Conjugate
R718
Host Species
Mouse
Target Species
Human
Content And Storage
Refrigerate Upon Arrival
Clone
WM53
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Primary or Secondary
Primary
Description
The WM53 monoclonal antibody specifically recognizes CD33 which is also known as Sialic acid-binding Ig-like lectin 3 (Siglec-3) or gp67
CD33 is a 67 kDa type I transmembrane glycoprotein that is variably expressed on myeloid progenitors, monocytes, macrophages, dendritic cells, neutrophils, basophils, mast cells, and on some activated T cells and NK cells
Normal lymphocytes, platelets, erythrocytes and pluripotent hematopoietic stem cells do not express the CD33 antigen
This glycoprotein reportedly functions as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.