7215186

Phospho-MSK1 (Thr581) Recombinant Rabbit Monoclonal Antibody (MSK1T581-A5), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-MSK1 (Thr581)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

O75582, Q8C050

Gene ID (Entrez)

314384, 73086, 9252

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Rps6ka5

Clone

MSK1T581-A5

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Gene Symbols

Rps6ka5

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Description

  • RPS6KA5 (MSK1) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes
  • RPS6KA5 is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes
  • Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin
  • Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression
  • In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress
  • In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential.

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Fischer Scientific

7215186

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MSK1 (Thr581)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
O75582, Q8C050

Gene ID (Entrez):
314384, 73086, 9252

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Rps6ka5

Clone:
MSK1T581-A5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Gene Symbols:
Rps6ka5

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215187

Rabbit Recombinant Monoclonal Antib...


Antigen:
SARS-CoV-2 Nucleocapsid

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Virus

Gene Accession No.:
P0DTC9

Gene ID (Entrez):
43740575

Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
N

Clone:
85C1

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.02% sodium azide

Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N

Gene Symbols:
N

Isotype:
IgG κ

Purification Method:
Protein A

Product Type:
Antibody

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Fischer Scientific

7215188

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-c-Cbl (Tyr700)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P22681, P22682

Gene ID (Entrez):
12402, 500985, 867

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr700 of human phospho c-Cbl.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Cbl

Clone:
CblY700-E1

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols:
Cbl

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215188

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-c-Cbl (Tyr700)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P22681, P22682

Gene ID (Entrez):
12402, 500985, 867

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr700 of human phospho c-Cbl.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Cbl

Clone:
CblY700-E1

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols:
Cbl

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody