7215200

Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Btk (Tyr551)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias

agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency

Gene Symbols

BTK

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

BtkY551-G12

Applications

ELISA, Flow Cytometry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q06187

Gene ID (Entrez)

695

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk.

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

BTK

Description

  • Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases
  • Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders
  • It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9
  • The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens
  • BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.

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Fischer Scientific

7215200

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Btk (Tyr551)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency

Gene Symbols:
BTK

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
BtkY551-G12

Applications:
ELISA, Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q06187

Gene ID (Entrez):
695

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
BTK

Img

Fischer Scientific

7215204

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MARCKS (Ser167, Ser170)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain

Gene Symbols:
MARCKS

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
MARCKSS167170-C9

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P26645, P29966, P30009

Gene ID (Entrez):
17118, 25603, 4082

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
MARCKS

Img

Fischer Scientific

7215204

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MARCKS (Ser167, Ser170)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain

Gene Symbols:
MARCKS

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
MARCKSS167170-C9

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P26645, P29966, P30009

Gene ID (Entrez):
17118, 25603, 4082

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
MARCKS

Img

Fischer Scientific

7215207

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Lck (Tyr505)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16

Gene Symbols:
LCK

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
LckY505-A3

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P06239

Gene ID (Entrez):
3932

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr505 of human phospho Lck.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
LCK