7215213

Phospho-Stat5 (Tyr694) Recombinant Rabbit Monoclonal Antibody (Stat5Y694-B5), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Stat5 (Tyr694)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias

AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols

STAT5A

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

Stat5Y694-B5

Applications

Flow Cytometry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P42229, P42230

Gene ID (Entrez)

20850, 6776

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

STAT5A

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Description

  • STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

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Img

Fischer Scientific

7215213

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Stat5 (Tyr694)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols:
STAT5A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
Stat5Y694-B5

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42229, P42230

Gene ID (Entrez):
20850, 6776

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
STAT5A

Img

Fischer Scientific

7215214

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-mTOR (Ser2448)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

Gene Symbols:
MTOR

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
mTORS2448-E11

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42345, Q9JLN9

Gene ID (Entrez):
2475, 56717

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MTOR

Img

Fischer Scientific

7215214

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-mTOR (Ser2448)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

Gene Symbols:
MTOR

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
mTORS2448-E11

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42345, Q9JLN9

Gene ID (Entrez):
2475, 56717

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MTOR

Img

Fischer Scientific

7215215

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-4EBP1 (Thr37, Thr46)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Gene Symbols:
EIF4EBP1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
4EB1T37T46-A5

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q13541, Q60876, Q62622

Gene ID (Entrez):
116636, 13685, 1978

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
EIF4EBP1