7215217

Phospho-c-Cbl (Tyr774) Recombinant Rabbit Monoclonal Antibody (CblY774-R3B8), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-c-Cbl (Tyr774)

Applications

Flow Cytometry

Conjugate

PE

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P22681, P22682

Gene ID (Entrez)

12402, 867

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human phospho c-Cbl.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Cbl

Clone

CblY774-R3B8

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols

Cbl

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Description

  • Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation
  • Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed)
  • Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation
  • Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.

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Img

Fischer Scientific

7215217

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-c-Cbl (Tyr774)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P22681, P22682

Gene ID (Entrez):
12402, 867

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human phospho c-Cbl.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Cbl

Clone:
CblY774-R3B8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols:
Cbl

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215218

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-4EBP1 (Thr37, Thr46)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q13541, Q60876, Q62622

Gene ID (Entrez):
116636, 13685, 1978

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
EIF4EBP1

Clone:
4EB1T37T46-A5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Gene Symbols:
EIF4EBP1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215218

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-4EBP1 (Thr37, Thr46)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q13541, Q60876, Q62622

Gene ID (Entrez):
116636, 13685, 1978

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
EIF4EBP1

Clone:
4EB1T37T46-A5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Gene Symbols:
EIF4EBP1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215218

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-4EBP1 (Thr37, Thr46)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q13541, Q60876, Q62622

Gene ID (Entrez):
116636, 13685, 1978

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
EIF4EBP1

Clone:
4EB1T37T46-A5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Gene Symbols:
EIF4EBP1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody