7215225
Phospho-Jak3 (Tyr980, Tyr981) Recombinant Rabbit Monoclonal Antibody (JAK3Y980981-E10), FITC, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-Jak3 (Tyr980, Tyr981)
Applications
Flow Cytometry
Conjugate
FITC
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P52333
Gene ID (Entrez)
3718
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3.
Primary or Secondary
Primary
Content And Storage
4° C, store in dark
Gene
JAK3
Clone
JAK3Y980981-E10
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil
Gene Symbols
JAK3
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Description
- Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
- JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
- In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
- The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
- Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
- JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
- However, active JAK1 may be required for complex responses
- Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.
Compare Similar Items
Show Difference
Antigen: Phospho-Jak3 (Tyr980, Tyr981)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P52333
Gene ID (Entrez): 3718
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: JAK3
Clone: JAK3Y980981-E10
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil
Gene Symbols: JAK3
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Jak3 (Tyr980, Tyr981)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P52333
Gene ID (Entrez):
3718
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
JAK3
Clone:
JAK3Y980981-E10
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil
Gene Symbols:
JAK3
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-MKK7 (Ser271, Thr275)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O14733
Gene ID (Entrez): 5609
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: MAP2K7
Clone: MKK7S271T275-R4F9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 2; 5930412N11Rik; c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; EMBL:AAX61178.1}; JN; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAP2K4; map2k7; map2k7 {ECO:0000312; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MAPKK 7; MAPKK7; MEK; MEK 4; MEK 7; Mek7; mitogen activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7; Mkk7; PRKMK7; protein kinase, mitogen activated, kinase 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SAPKK4; SAPKK-4; SEK1; sek2; SKK4; Stress-activated protein kinase kinase 4
Gene Symbols: MAP2K7
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-MKK7 (Ser271, Thr275)
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O14733
Gene ID (Entrez):
5609
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
MAP2K7
Clone:
MKK7S271T275-R4F9
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
2; 5930412N11Rik; c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; EMBL:AAX61178.1}; JN; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAP2K4; map2k7; map2k7 {ECO:0000312; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MAPKK 7; MAPKK7; MEK; MEK 4; MEK 7; Mek7; mitogen activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7; Mkk7; PRKMK7; protein kinase, mitogen activated, kinase 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SAPKK4; SAPKK-4; SEK1; sek2; SKK4; Stress-activated protein kinase kinase 4
Gene Symbols:
MAP2K7
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-MAP2K4 (Ser257)
Applications: Flow Cytometry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse, Non-human Primate
Gene Accession No.: P45985, P47809
Gene ID (Entrez): 26398, 6416
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: MAP2K4
Clone: SEK1MKK4S257-C5
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias: C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Gene Symbols: MAP2K4
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-MAP2K4 (Ser257)
Applications:
Flow Cytometry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse, Non-human Primate
Gene Accession No.:
P45985, P47809
Gene ID (Entrez):
26398, 6416
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
MAP2K4
Clone:
SEK1MKK4S257-C5
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Gene Symbols:
MAP2K4
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: SARS-CoV-2 Nucleocapsid
Applications: ELISA, Functional Assay, Surface Plasmon Resonance
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Virus
Gene Accession No.: P0DTC9
Gene ID (Entrez): 43740575
Immunogen: HK293 derived SARS-COV-2 Nucleocapsid corresponding to amino acids 2-419.
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Gene: N
Clone: 4D0J7
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.1% Braveds MB-1; pH 7.4
Gene Alias: COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols: N
Isotype: IgG
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
SARS-CoV-2 Nucleocapsid
Applications:
ELISA, Functional Assay, Surface Plasmon Resonance
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Virus
Gene Accession No.:
P0DTC9
Gene ID (Entrez):
43740575
Immunogen:
HK293 derived SARS-COV-2 Nucleocapsid corresponding to amino acids 2-419.
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Gene:
N
Clone:
4D0J7
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.1% Braveds MB-1; pH 7.4
Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols:
N
Isotype:
IgG
Purification Method:
Affinity chromatography
Product Type:
Antibody