7215234
Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-F10), APC, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-Chk1 (Ser317)
Applications
Flow Cytometry
Conjugate
APC
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O14757, O35280
Gene ID (Entrez)
1111, 12649
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Primary or Secondary
Primary
Content And Storage
4° C
Gene
Chek1
Clone
Chk1S317-F10
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Gene Symbols
Chek1
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Description
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Phospho-Chk1 (Ser317)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O14757, O35280
Gene ID (Entrez): 1111, 12649
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: Chek1
Clone: Chk1S317-F10
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Gene Symbols: Chek1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Chk1 (Ser317)
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O14757, O35280
Gene ID (Entrez):
1111, 12649
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
Chek1
Clone:
Chk1S317-F10
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Gene Symbols:
Chek1
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: SARS-CoV-2 Nucleocapsid
Applications: ELISA
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Virus
Gene Accession No.: P0DTC9
Gene ID (Entrez): 43740575
Immunogen: SARS-CoV-2 nucleoprotein (NP) specific peptide.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: N
Clone: 84C4A
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.02% sodium azide
Gene Alias: COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols: N
Isotype: IgG κ
Purification Method: Protein A
Product Type: Antibody
Antigen:
SARS-CoV-2 Nucleocapsid
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Virus
Gene Accession No.:
P0DTC9
Gene ID (Entrez):
43740575
Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
N
Clone:
84C4A
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.02% sodium azide
Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols:
N
Isotype:
IgG κ
Purification Method:
Protein A
Product Type:
Antibody
Antigen: Phospho-Akt1 (Ser473)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P31749, P31750
Gene ID (Entrez): 11651, 207
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser473 of human phospho Akt1.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: AKT1
Clone: AktS473-B9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Gene Symbols: AKT1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Akt1 (Ser473)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P31749, P31750
Gene ID (Entrez):
11651, 207
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser473 of human phospho Akt1.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
AKT1
Clone:
AktS473-B9
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Gene Symbols:
AKT1
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-Rb (Ser807, Ser811)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P06400, P13405
Gene ID (Entrez): 19645, 5925
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser807/811 of human phospho-Rb.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: RB1
Clone: RbS807S811-D9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols: RB1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Rb (Ser807, Ser811)
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P06400, P13405
Gene ID (Entrez):
19645, 5925
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser807/811 of human phospho-Rb.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
RB1
Clone:
RbS807S811-D9
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols:
RB1
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody