7215301

Phospho-Stat5 (Tyr694) Recombinant Rabbit Monoclonal Antibody (Stat5Y694-G11), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-Stat5 (Tyr694)

Applications

Flow Cytometry

Conjugate

FITC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P42229, P42230

Gene ID (Entrez)

20850, 6776

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary

Primary

Content And Storage

4° C, store in dark

Gene

STAT5A

Clone

Stat5Y694-G11

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols

STAT5A

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Description

  • STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

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Img

Fischer Scientific

7215301

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Stat5 (Tyr694)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42229, P42230

Gene ID (Entrez):
20850, 6776

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
STAT5A

Clone:
Stat5Y694-G11

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols:
STAT5A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215305

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-KSR1 (Ser392)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q61097, Q8IVT5

Gene ID (Entrez):
16706, 8844

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
KSR1

Clone:
KSR1S392-3A4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Gene Symbols:
KSR1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215305

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-KSR1 (Ser392)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q61097, Q8IVT5

Gene ID (Entrez):
16706, 8844

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
KSR1

Clone:
KSR1S392-3A4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Gene Symbols:
KSR1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215305

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-KSR1 (Ser392)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q61097, Q8IVT5

Gene ID (Entrez):
16706, 8844

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
KSR1

Clone:
KSR1S392-3A4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Gene Symbols:
KSR1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody