7218461

Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), eFluor™ 506, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Ly-6G/Ly-6C

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

Gene Symbols

Ly6c1, Ly6c2, Ly6g

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

RB6-8C5

Applications

Flow Cytometry

Conjugate

eFluor 506

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P0CW02, P0CW03, P35461

Gene ID (Entrez)

100041546, 17067, 546644

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • The RB6-8C5 MAb reacts with mouse Ly-6G, a 21-25 kDa protein also known as the myeloid differentiation antigen Gr-1
  • A GPI-linked protein, Gr-1 is expressed by the myeloid lineage in a developmentally regulated manner in the bone marrow
  • While monocytes only express Gr-1 transiently during their bone marrow development, the expression of Gr-1 on bone marrow granulocytes as well as on peripheral neutrophils is a good marker for these populations
  • eBioscience testing indicates that in the bone marrow and lysed whole blood, the antibody clone RB6-8C5 also stains cells that express the highest levels of Ly6c (as defined by staining with antibody clone HK1.4)
  • It is recommended that 1A8-Ly6G (cat
  • 9668) be used when looking at Ly-6G specific targets
  • Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm
  • They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments
  • In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes
  • Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.

Compare Similar Items

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Fischer Scientific

7218461

Rat Monoclonal Antibody...


Antigen:
Ly-6G/Ly-6C

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

Gene Symbols:
Ly6c1, Ly6c2, Ly6g

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
RB6-8C5

Applications:
Flow Cytometry

Conjugate:
eFluor 506

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P0CW02, P0CW03, P35461

Gene ID (Entrez):
100041546, 17067, 546644

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7218463

Mouse Monoclonal Antibody...


Antigen:
CD4

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
RPA-T4

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 561

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01730

Gene ID (Entrez):
920

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7218474

Rat Isotype Control...


Antigen:
Rat IgG2a kappa

Concentration:
1 mg/mL

Classification:
__

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2

Gene Symbols:
__

Primary or Secondary:
Isotype Control (Primary)

Content And Storage:
4° C

Clone:
eBR2a

Applications:
__

Conjugate:
Functional Grade

Host Species:
Rat

Target Species:
__

Gene Accession No.:
__

Gene ID (Entrez):
__

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
__

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Fischer Scientific

7218479

Mouse Monoclonal Antibody...


Antigen:
CD368 (Clec6)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD368; Clec4d; CLEC6; CLEC-6; CLECSF8; CLECSF8Mpcl; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8; C-type lectin domain family 4 member D; C-type lectin domain family 4, member d; C-type lectin receptor; C-type lectin superfamily member 8; C-type lectin, superfamily member 8; C-type lectin-like receptor 6; macrophage C-type lectin; macrophage-restricted C-type lectin; Mcl; MGC40078; Mpcl; superfamilymember 8

Gene Symbols:
CLEC4D

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
9B9

Applications:
Flow Cytometry

Conjugate:
eFluor 660

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8WXI8

Gene ID (Entrez):
338339

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody