7218537
CD101 Monoclonal Antibody (BB27), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD101
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Gene Accession No.
Q93033
Gene ID (Entrez)
9398
Isotype
IgG1
Purification Method
Affinity chromatography
Gene
CD101
Clone
BB27
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Alias
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Gene Symbols
CD101
Primary or Secondary
Primary
Product Type
Antibody
Description
- The MAb BB27 reacts to human CD101 also known as V7 antigen, a member of the Ig superfamily
- CD101 is a disulfide linked homodimer of unknown function
- Expression of CD101 is found on monocytes, granulocytes and dendritic cells (Langerhan-like cells HLA-DR, CD1a, CD1c)
- In addition expression on T lymphocytes is important for cell activation
- CD101+ CD28+ cells are very responsive to CD28 signaling
- In combination with anti-CD28 or suboptimal levels of anti-CD3, anti-CD101 can increase proliferation thereby suggesting an activating role
- The MAb BB27 has been shown to inhibit the T cell reactivity in allogeneic and antigen-specific mixed DC-T cell cultures
- Recently it has been demonstrated that mouse CD101 is found on a subpopulation of regulatory T cells (CD4, CD25, Foxp3 positive) that have high suppressor activity
- Expression of CD101 on human PBMCs shows staining of about 30% of the Foxp3 positive cells
- Studies have not confirmed higher suppressor activity in the human CD101 population
- CD101 also known as V7 antigen, a member of the Ig superfamily
- CD101 is a disulfide linked homodimer of unknown function
- Expression of CD101 is found on monocytes, granulocytes and dendritic cells (Langerhan-like cells HLA-DR, CD1a, CD1c)
- In addition expression on T lymphocytes is important for cell activation
- CD101+ CD28+ cells are very responsive to CD28 signaling
- In combination with anti-CD28 or suboptimal levels of anti-CD3, anti-CD101 can increase proliferation thereby suggesting an activating role
- The monoclonal antibody BB27 has been shown to inhibit the T cell reactivity in allogeneic and antigen-specific mixed DC-T cell cultures
- Recently it has been demonstrated that mouse CD101 is found on a subpopulation of regulatory T cells (CD4, CD25, Foxp3 positive) that have high suppressor activity
- Expression of CD101 on human PBMCs shows staining of about 30% of the Foxp3 positive cells
- Studies have not confirmed higher suppressor activity in the human CD101 population.
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Antigen: CD101
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: Q93033
Gene ID (Entrez): 9398
Isotype: IgG1
Purification Method: Affinity chromatography
Gene: CD101
Clone: BB27
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Alias: Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Gene Symbols: CD101
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CD101
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
Q93033
Gene ID (Entrez):
9398
Isotype:
IgG1
Purification Method:
Affinity chromatography
Gene:
CD101
Clone:
BB27
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Alias:
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Gene Symbols:
CD101
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Phospho-SRC (Tyr418)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P05480, P12931
Gene ID (Entrez): 20779, 6714
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Gene: SRC
Clone: SC1T2M3
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Alias: ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc
Gene Symbols: SRC
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Phospho-SRC (Tyr418)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P05480, P12931
Gene ID (Entrez):
20779, 6714
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Gene:
SRC
Clone:
SC1T2M3
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc
Gene Symbols:
SRC
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Alpha-Smooth Muscle Actin
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P62736, P62737, P62738
Gene ID (Entrez): 11475, 59, 81633
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: ACTA2
Clone: 1A4
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse, Rat
Gene Alias: 0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg
Gene Symbols: ACTA2
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Alpha-Smooth Muscle Actin
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P62736, P62737, P62738
Gene ID (Entrez):
11475, 59, 81633
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
ACTA2
Clone:
1A4
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse, Rat
Gene Alias:
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg
Gene Symbols:
ACTA2
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Nanog
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: Q80Z64
Gene ID (Entrez): 71950
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: NANOG
Clone: eBioMLC-51
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate: eFluor 660
Host Species: Rat
Target Species: Mouse
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Gene Symbols: NANOG
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Nanog
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
Q80Z64
Gene ID (Entrez):
71950
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
NANOG
Clone:
eBioMLC-51
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate:
eFluor 660
Host Species:
Rat
Target Species:
Mouse
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Gene Symbols:
NANOG
Primary or Secondary:
Primary
Product Type:
Antibody