7226367
cGAS Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
cGAS
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q8N884
Gene ID (Entrez)
115004
Immunogen
Glu225-Lys407
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
CGAS
Concentration
0.98 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
C6orf150; h-cGAS; MB21D1
Gene Symbols
CGAS
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity
- Catalysis involves both the formation of 2', 5' phosphodiester linkage at the GpA step and the formation of 3', 5' phosphodiester linkage at the ApG step
- This produces c[G(2',5')pA(3'5')p] responses
- cGAS also binds cytosolic DNA directly, leading to the activation and synthesis of cGAMP
- Then, a second messenger binds to and activates TMEM173/STING thereby triggering type-I interferon production
- cGAS is also involved in innate immune sensorship of infection, detection of DNA from bacteria, response to cellular stress, DNA damage, and regulation of cellular senescence.
Compare Similar Items
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Antigen: cGAS
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8N884
Gene ID (Entrez): 115004
Immunogen: Glu225-Lys407
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: CGAS
Concentration: 0.98 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: C6orf150; h-cGAS; MB21D1
Gene Symbols: CGAS
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
cGAS
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8N884
Gene ID (Entrez):
115004
Immunogen:
Glu225-Lys407
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
CGAS
Concentration:
0.98 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
C6orf150; h-cGAS; MB21D1
Gene Symbols:
CGAS
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Calmodulin
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P0DP23, P0DP24, P0DP25
Gene ID (Entrez): 801, 805, 808
Immunogen: Met1-Lys149 (Accession P62158), with N-terminal His and GST Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: __
Concentration: 0.55 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142
Gene Symbols: Calm1, Calm2, CALM3
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
Calmodulin
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P0DP23, P0DP24, P0DP25
Gene ID (Entrez):
801, 805, 808
Immunogen:
Met1-Lys149 (Accession P62158), with N-terminal His and GST Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
__
Concentration:
0.55 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142
Gene Symbols:
Calm1, Calm2, CALM3
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Calmodulin
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P0DP23, P0DP24, P0DP25
Gene ID (Entrez): 801, 805, 808
Immunogen: Met1-Lys149 (Accession P62158), with N-terminal His and GST Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: __
Concentration: 0.55 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142
Gene Symbols: Calm1, Calm2, CALM3
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
Calmodulin
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P0DP23, P0DP24, P0DP25
Gene ID (Entrez):
801, 805, 808
Immunogen:
Met1-Lys149 (Accession P62158), with N-terminal His and GST Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
__
Concentration:
0.55 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142
Gene Symbols:
Calm1, Calm2, CALM3
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Carboxypeptidase A4
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9UI42
Gene ID (Entrez): 51200
Immunogen: Lys55-Tyr421 (Accession Q9UI42), with N-terminal His Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: CPA4
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 1110019K20Rik; AV009555; Carboxypeptidase A3; carboxypeptidase A4; CPA3; Cpa4; RGD1563619; UNQ694/PRO1339
Gene Symbols: CPA4
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
Carboxypeptidase A4
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9UI42
Gene ID (Entrez):
51200
Immunogen:
Lys55-Tyr421 (Accession Q9UI42), with N-terminal His Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
CPA4
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
1110019K20Rik; AV009555; Carboxypeptidase A3; carboxypeptidase A4; CPA3; Cpa4; RGD1563619; UNQ694/PRO1339
Gene Symbols:
CPA4
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody