HFE2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
HFE2
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q6ZVN8
Gene ID (Entrez)
148738
Immunogen
Lys234-Ser416 (Accession Q6ZVN8), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
HFE2
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC
Gene Symbols
HFE2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- HFE2 is involved in iron metabolism
- It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression
- It could also represent the cellular receptor for hepcidin
- Alternatively spliced transcript variants encoding different isoforms have been identified for this gene
- Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH)
- JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
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Antigen: HFE2
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q6ZVN8
Gene ID (Entrez): 148738
Immunogen: Lys234-Ser416 (Accession Q6ZVN8), with N-terminal His Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: HFE2
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC
Gene Symbols: HFE2
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
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