7228663

CD19 Monoclonal Antibody (eBio1D3 (1D3)), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD19

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Gene Symbols

Cd19

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Cd19

Clone

eBio1D3 (1D3)

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 395

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P25918

Gene ID (Entrez)

12478

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • CD19 is a member of the immunoglobulin superfamily and has two Ig like domains
  • The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains
  • CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage
  • Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen
  • The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias
  • Lymphocytes proliferate and differentiate in response to various concentrations of different antigens
  • The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors
  • CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation
  • Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge
  • Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

Compare Similar Items

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Img

Fischer Scientific

7228663

Rat Monoclonal Antibody...


Antigen:
CD19

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Gene Symbols:
Cd19

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cd19

Clone:
eBio1D3 (1D3)

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P25918

Gene ID (Entrez):
12478

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Rat Monoclonal Antibody...


Antigen:
CD335 (NKp46)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1

Gene Symbols:
NCR1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
NCR1

Clone:
29A1.4

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q8C567

Gene ID (Entrez):
17086

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD28

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44

Gene Symbols:
Cd28

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cd28

Clone:
CD28.2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 480

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10747

Gene ID (Entrez):
940

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7228669

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Antigen:
CD28

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44

Gene Symbols:
Cd28

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cd28

Clone:
CD28.2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 480

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10747

Gene ID (Entrez):
940

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody