7240377

CD74 Recombinant Rabbit Monoclonal Antibody (301), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD74

Concentration

1 mg/mL

Classification

Recombinant Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33

Gene Symbols

CD74

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

Clone

301

Applications

ELISA

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P04233

Gene ID (Entrez)

972

Immunogen

Recombinant Human CD74 protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

CD74

Related Products

Img

Fischer Scientific

7238697

Rabbit Monoclonal Antibody...

Img

Fischer Scientific

7238697

Rabbit Monoclonal Antibody...

Img

Fischer Scientific

7244781

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7244890

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7244890

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7240578

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7241365

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7240543

Rabbit Recombinant Monoclonal Antib...

Description

  • Specificity: Human CD74 HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB)
  • The alpha chain gene contains 5 exons
  • Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
  • DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes
  • Three loci, DR, DQ and DP, encode the major expressed products of the human class II region
  • The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240377

Rabbit Recombinant Monoclonal Antib...


Antigen:
CD74

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33

Gene Symbols:
CD74

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
301

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P04233

Gene ID (Entrez):
972

Immunogen:
Recombinant Human CD74 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CD74

Img

Fischer Scientific

7240378

Rabbit Recombinant Monoclonal Antib...


Antigen:
IFN gamma

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Gene Symbols:
IFNG

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
238

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01579

Gene ID (Entrez):
3458

Immunogen:
Recombinant Human Interferon Gamma/IFN gamma/IFNG Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
IFNG

Img

Fischer Scientific

7240380

Mouse Monoclonal Antibody...


Antigen:
CCL1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
BF534335; C-C motif chemokine 1; C-C motif chemokine ligand 1; CCL 1; Ccl1; CCR8 ligand; chemokine (C-C motif) ligand 1; I-309; inflammatory cytokine I-309; P500; SCYA1; SISe; SIS-epsilon; small inducible cytokine A1; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); small-inducible cytokine A1; T lymphocyte-secreted protein I-309; TCA3; TCA-3; T-cell activation protein 3

Gene Symbols:
CCL1

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

Clone:
01

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P22362

Gene ID (Entrez):
6346

Immunogen:
Recombinant Human I-309/CCL1 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CCL1

Img

Fischer Scientific

7240380

Mouse Monoclonal Antibody...


Antigen:
CCL1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
BF534335; C-C motif chemokine 1; C-C motif chemokine ligand 1; CCL 1; Ccl1; CCR8 ligand; chemokine (C-C motif) ligand 1; I-309; inflammatory cytokine I-309; P500; SCYA1; SISe; SIS-epsilon; small inducible cytokine A1; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); small-inducible cytokine A1; T lymphocyte-secreted protein I-309; TCA3; TCA-3; T-cell activation protein 3

Gene Symbols:
CCL1

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

Clone:
01

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P22362

Gene ID (Entrez):
6346

Immunogen:
Recombinant Human I-309/CCL1 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CCL1