7240411

PDI Monoclonal Antibody (2F6G12H2), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PDI

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C

Gene Symbols

P4hb

Isotype

IgG1

Purification Method

Protein A

Product Type

Antibody

Clone

2F6G12H2

Applications

ELISA, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P07237

Gene ID (Entrez)

5034

Immunogen

Recombinant Human P4HB protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

P4hb

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Description

  • Specificity: Human P4HB/ERBA2L Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds
  • At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell
  • It may therefore cause structural modifications of exofacial proteins
  • Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins
  • At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins
  • At low concentrations, it facilitates aggregation (anti-chaperone activity)
  • PDI may be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis
  • It also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP
  • Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.

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Fischer Scientific

7240411

Mouse Monoclonal Antibody...


Antigen:
PDI

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C

Gene Symbols:
P4hb

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
2F6G12H2

Applications:
ELISA, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P07237

Gene ID (Entrez):
5034

Immunogen:
Recombinant Human P4HB protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
P4hb

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7240413

Rabbit Recombinant Monoclonal Antib...


Antigen:
CD7

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

Gene Symbols:
CD7

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
15

Applications:
ELISA, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P09564

Gene ID (Entrez):
924

Immunogen:
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Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CD7

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Antigen:
CD7

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

Gene Symbols:
CD7

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
15

Applications:
ELISA, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P09564

Gene ID (Entrez):
924

Immunogen:
Recombinant Human CD7 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CD7

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Antigen:
CD105

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Gene Symbols:
ENG

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
029

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q63961

Gene ID (Entrez):
13805

Immunogen:
Recombinant Mouse Endoglin/CD105 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
ENG