7240425

TrkB Recombinant Rabbit Monoclonal Antibody (107), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

TrkB

Concentration

1 mg/mL

Classification

Recombinant Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B

Gene Symbols

Ntrk2

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

Clone

107

Applications

ELISA

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q16620

Gene ID (Entrez)

4915

Immunogen

Recombinant Human Trk-B protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

Ntrk2

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Description

  • Specificity: Human NTRK2/Trk-B NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF)
  • Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses
  • TrkB is involved in the development and maintenance of the nervous system
  • Moreover, Trk B is a tyrosine kinase gene highly related to Trk A
  • Trk B expression is confined to tissues within the central and peripheral nervous systems
  • The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3
  • TrkB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • Signaling through TrkB leads to cell differentiation
  • Mutations in the TrkB gene have been associated with obesity and mood disorders
  • Alternate transcriptional splice variants encoding different isoforms have been found for the TrkB gene.

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Antigen:
TrkB

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B

Gene Symbols:
Ntrk2

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
107

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q16620

Gene ID (Entrez):
4915

Immunogen:
Recombinant Human Trk-B protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Ntrk2

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Antigen:
TREM2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
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Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; Trem2; TREM-2; Trem2a; Trem2b; Trem2c; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c

Gene Symbols:
Trem2

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
08

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q9NZC2

Gene ID (Entrez):
54209

Immunogen:
Recombinant Human TREM-2/TREM2 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Trem2

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Antigen:
CXCL5

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AMCF-II; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine ligand 5; CXCL; CXCL5; Cxcl6; Cytokine LIX; ENA78; ENA-78; ENA-78(1-78); ENA-78(8-78); ENA-78(9-78); Epithelial-derived neutrophil-activating protein 78; GCP-2; GCP-2(1-78); GCP-2(9-78); granulocyte chemotactic protein-2; LIX; Neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; Scyb5; Scyb6; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); small inducible cytokine subfamily B, member 15; small-inducible cytokine B5

Gene Symbols:
CXCL5

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
14

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P42830

Gene ID (Entrez):
6374

Immunogen:
Recombinant Human CXCL5 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CXCL5

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Antigen:
CXCL5

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AMCF-II; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine ligand 5; CXCL; CXCL5; Cxcl6; Cytokine LIX; ENA78; ENA-78; ENA-78(1-78); ENA-78(8-78); ENA-78(9-78); Epithelial-derived neutrophil-activating protein 78; GCP-2; GCP-2(1-78); GCP-2(9-78); granulocyte chemotactic protein-2; LIX; Neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; Scyb5; Scyb6; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); small inducible cytokine subfamily B, member 15; small-inducible cytokine B5

Gene Symbols:
CXCL5

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
14

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P42830

Gene ID (Entrez):
6374

Immunogen:
Recombinant Human CXCL5 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CXCL5