7240502

TIM-1 Monoclonal Antibody (12B1C8H3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

TIM-1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols

Havcr1

Isotype

IgG1

Purification Method

Protein A

Product Type

Antibody

Clone

12B1C8H3

Applications

ELISA

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q96D42

Gene ID (Entrez)

26762

Immunogen

Recombinant Human HAVCR1 protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

Havcr1

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Description

  • Specificity: Human HAVCR1/TIM1/KIM1 CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail
  • The endogenous ligand for CD365 is Tim-4
  • In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus
  • The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes
  • Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity
  • CD365 has also been implicated in the T cell co-stimulation
  • CD365 is primarily expressed in epithelial cells
  • It is also highly expressed in A549, 769-P and Caco-2 and cell lines
  • CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240502

Mouse Monoclonal Antibody...


Antigen:
TIM-1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols:
Havcr1

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
12B1C8H3

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96D42

Gene ID (Entrez):
26762

Immunogen:
Recombinant Human HAVCR1 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Havcr1

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Mouse Monoclonal Antibody...


Antigen:
Angiopoietin 2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AGPT2; Ang2; Ang-2; angiopoietin 2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; ANGPT2; endothelial growth factor; Tie2-ligand

Gene Symbols:
ANGPT2

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
07

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O15123

Gene ID (Entrez):
285

Immunogen:
Recombinant Human Angiopoietin-2 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
ANGPT2

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Mouse Monoclonal Antibody...


Antigen:
Angiopoietin 2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AGPT2; Ang2; Ang-2; angiopoietin 2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; ANGPT2; endothelial growth factor; Tie2-ligand

Gene Symbols:
ANGPT2

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
07

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O15123

Gene ID (Entrez):
285

Immunogen:
Recombinant Human Angiopoietin-2 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
ANGPT2

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Antigen:
SPARCL1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Ecm2; Extracellular matrix protein 2; hevin; High endothelial venule protein; MAST 9; MAST9; matrix glycoprotein Sc1; PIG33; proliferation-inducing protein 33; SC1; SPARC like 1; SPARCL1; SPARC-like 1; SPARC-like 1 (hevin); SPARC-like 1 (mast9, hevin); SPARC-like protein 1

Gene Symbols:
SPARCL1

Isotype:
IgG2b

Purification Method:
Protein A

Product Type:
Antibody

Clone:
05

Applications:
Flow Cytometry, Immunocytochemistry

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q14515

Gene ID (Entrez):
8404

Immunogen:
Recombinant Human SPARCL1/SPARC-like 1 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
SPARCL1