7240555

CD86 (B7-2) Monoclonal Antibody (12), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD86 (B7-2)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Gene Symbols

CD86

Isotype

IgG1

Purification Method

Protein A

Product Type

Antibody

Clone

12

Applications

ELISA

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

0

Gene ID (Entrez)

56822

Immunogen

Recombinant Rat CD86/B7-2 Protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

CD86

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Description

  • Specificity: Rat CD86/B7-2 CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240555

Mouse Monoclonal Antibody...


Antigen:
CD86 (B7-2)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Gene Symbols:
CD86

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
12

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
0

Gene ID (Entrez):
56822

Immunogen:
Recombinant Rat CD86/B7-2 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CD86

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Fischer Scientific

7240556

Mouse Monoclonal Antibody...


Antigen:
PCSK9

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9

Gene Symbols:
PCSK9

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
15

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8NBP7

Gene ID (Entrez):
255738

Immunogen:
Recombinant Human PCSK9 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
PCSK9

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7240557

Rabbit Recombinant Monoclonal Antib...


Antigen:
SPINK4

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
epididymis luminal protein 136; gastrointestinal peptide; HEL136; PEC60; PEC-60; Peptide PEC-60 homolog; serine peptidase inhibitor, Kazal type 4; serine protease inhibitor Kazal-type 4; serine protease inhibitor, Kazal type 4; SPINK4

Gene Symbols:
SPINK4

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
265

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O60575

Gene ID (Entrez):
27290

Immunogen:
Recombinant Human SPINK4 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
SPINK4

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7240559

Mouse Monoclonal Antibody...


Antigen:
CXCL5

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AMCF-II; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine ligand 5; CXCL; CXCL5; Cxcl6; Cytokine LIX; ENA78; ENA-78; ENA-78(1-78); ENA-78(8-78); ENA-78(9-78); Epithelial-derived neutrophil-activating protein 78; GCP-2; GCP-2(1-78); GCP-2(9-78); granulocyte chemotactic protein-2; LIX; Neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; Scyb5; Scyb6; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); small inducible cytokine subfamily B, member 15; small-inducible cytokine B5

Gene Symbols:
CXCL5

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
03

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P42830

Gene ID (Entrez):
6374

Immunogen:
Recombinant Human CXCL5 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CXCL5