7240812

RNASE3 Monoclonal Antibody (C5), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

RNASE3

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

cytotoxic ribonuclease; Ear11; EAR-11; Ear3; ECP; Eosinophil cationic protein; eosinophil cationic protein-like; eosinophil cationic-type ribonuclease 3; Eosinophil secondary granule ribonuclease 11; eosinophil-associated ribonuclease 3; eosinophil-associated, ribonuclease A family, member 3; LOC100361866; mR3; MR-3; murine ribonuclease 3; RAF1; Ribonuclease 3; ribonuclease A family member 3; ribonuclease, RNase A family 3; ribonuclease, RNase A family, 3; RNase 3; RNASE3; RNS3

Gene Symbols

RNASE3

Isotype

IgG2a κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C5

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P12724

Gene ID (Entrez)

6037

Immunogen

Pro30-Val154 (Accession P12724), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

RNASE3

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Description

  • ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family
  • ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system
  • ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils
  • ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities
  • It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death
  • ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240812

Mouse Monoclonal Antibody...


Antigen:
RNASE3

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
cytotoxic ribonuclease; Ear11; EAR-11; Ear3; ECP; Eosinophil cationic protein; eosinophil cationic protein-like; eosinophil cationic-type ribonuclease 3; Eosinophil secondary granule ribonuclease 11; eosinophil-associated ribonuclease 3; eosinophil-associated, ribonuclease A family, member 3; LOC100361866; mR3; MR-3; murine ribonuclease 3; RAF1; Ribonuclease 3; ribonuclease A family member 3; ribonuclease, RNase A family 3; ribonuclease, RNase A family, 3; RNase 3; RNASE3; RNS3

Gene Symbols:
RNASE3

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P12724

Gene ID (Entrez):
6037

Immunogen:
Pro30-Val154 (Accession P12724), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
RNASE3

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Rabbit Polyclonal Antibody...


Antigen:
SLIT3

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
b2b2362.1Clo; KIAA0814; Megf5; Multiple EGF-like domains protein 5; multiple epidermal growth factor-like domains 5; multiple epidermal growth factor-like domains protein 5; SLIL2; SLIL2FLJ10764; slit guidance ligand 3; slit homolog 3; slit homolog 3 (Drosophila); slit homolog 3 protein; SLIT1; slit2; SLIT3; Slit-3; UNQ691/PRO1336

Gene Symbols:
SLIT3

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Clone:
__

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O75094

Gene ID (Entrez):
6586

Immunogen:
Lys1405-Glu1512 (Accession O75094), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
SLIT3

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7240816

Mouse Monoclonal Antibody...


Antigen:
BMP-10

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
BMP; BMP10; BMP-10; bmp10 {ECO:0000312; bmp10b; Bone morphogenetic protein; bone morphogenetic protein 10; EMBL:BAE16990.1, ECO:0000312; RGD:1562986}; si:dkey-13n15.5

Gene Symbols:
BMP10

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
A1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O95393

Gene ID (Entrez):
27302

Immunogen:
Arg315-Arg424 (Accession O95393), with N-terminal His and GST Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
BMP10

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Antigen:
BMP-10

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
BMP; BMP10; BMP-10; bmp10 {ECO:0000312; bmp10b; Bone morphogenetic protein; bone morphogenetic protein 10; EMBL:BAE16990.1, ECO:0000312; RGD:1562986}; si:dkey-13n15.5

Gene Symbols:
BMP10

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
A1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O95393

Gene ID (Entrez):
27302

Immunogen:
Arg315-Arg424 (Accession O95393), with N-terminal His and GST Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
BMP10