7240836

CD16b (FCGR3B) Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD16b (FCGR3B)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

CD16; CD16B; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcR-10; FCRIII; FCRIIIb; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B

Gene Symbols

FCGR3B

Isotype

IgG2a κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

O75015

Gene ID (Entrez)

2215

Immunogen

Pro24-Ser203 (Accession O75015), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

FCGR3B

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Description

  • CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes
  • CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells
  • Human CD16 is expressed in two forms – FCGR3A and FCGR3B
  • FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity
  • Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit
  • Besides IgG, FCGR3A can be triggered also by oligomeric IgE
  • FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype
  • Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Compare Similar Items

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Img

Fischer Scientific

7240836

Mouse Monoclonal Antibody...


Antigen:
CD16b (FCGR3B)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
CD16; CD16B; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcR-10; FCRIII; FCRIIIb; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B

Gene Symbols:
FCGR3B

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O75015

Gene ID (Entrez):
2215

Immunogen:
Pro24-Ser203 (Accession O75015), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
FCGR3B

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7240837

Mouse Monoclonal Antibody...


Antigen:
Activin A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product

Gene Symbols:
Inhba

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
H9

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P08476

Gene ID (Entrez):
3624

Immunogen:
Gly311-Ser426 (Accession P08476), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
Inhba

Img

Fischer Scientific

7240837

Mouse Monoclonal Antibody...


Antigen:
Activin A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product

Gene Symbols:
Inhba

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
H9

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P08476

Gene ID (Entrez):
3624

Immunogen:
Gly311-Ser426 (Accession P08476), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
Inhba

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7240838

Mouse Monoclonal Antibody...


Antigen:
COL1A1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
alpha-1 type 1 collagen; alpha-1 type I collagen; alpha1(I) procollagen; COL1A; Col1a1; Col1a-1; Cola1; Cola-1; COLIA1; Collagen 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen type I alpha 1; collagen, type 1, alpha 1; collagen, type I, alpha 1; Collagen1A1; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; Type I Collagen; type I proalpha 1; type I procollagen alpha 1 chain; type I-alpha 1 collagen

Gene Symbols:
COL1A1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C3

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02452

Gene ID (Entrez):
1277

Immunogen:
Ala1218-Ile1440 (Accession P02452), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
COL1A1