7240854
Tankyrase 2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Tankyrase 2
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q9H2K2
Gene ID (Entrez)
80351
Immunogen
Ser959-Gly1166 (Accession Q9H2K2), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
TNKS2
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Gene Symbols
TNKS2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:11739745, PubMed:11802774, PubMed:19759537, PubMed:21478859, PubMed:23622245, PubMed:25043379)
- Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation (PubMed:19759537, PubMed:21478859)
- Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination (PubMed:21478859)
- Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length (PubMed:11739745)
- Stimulates 26S proteasome activity (PubMed:23622245)
- [UniProt]
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Antigen: Tankyrase 2
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9H2K2
Gene ID (Entrez): 80351
Immunogen: Ser959-Gly1166 (Accession Q9H2K2), with N-terminal His Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: TNKS2
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Gene Symbols: TNKS2
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
Tankyrase 2
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9H2K2
Gene ID (Entrez):
80351
Immunogen:
Ser959-Gly1166 (Accession Q9H2K2), with N-terminal His Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
TNKS2
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Gene Symbols:
TNKS2
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Aquaporin 4
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P55087
Gene ID (Entrez): 361
Immunogen: Cys178-Gly317 (Accession P55087), with N-terminal His and GST Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: AQP4
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols: AQP4
Isotype: IgG2a κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Aquaporin 4
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P55087
Gene ID (Entrez):
361
Immunogen:
Cys178-Gly317 (Accession P55087), with N-terminal His and GST Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
AQP4
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols:
AQP4
Isotype:
IgG2a κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: FAP
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q12884
Gene ID (Entrez): 2191
Immunogen: Ile523-Asp760 (Accession Q12884), with N-terminal His Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: FAP
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: 170 kDa melanoma membrane-bound gelatinase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE; Dipeptidyl peptidase FAP; DPPIV; Fap; FAPA; FAPalpha; fibroblast activation protein; fibroblast activation protein alpha; fibroblast activation protein, alpha; gelatine degradation protease FAP; Integral membrane serine protease; post-proline cleaving enzyme; Prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; Surface-expressed protease
Gene Symbols: FAP
Isotype: IgG2b κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
FAP
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q12884
Gene ID (Entrez):
2191
Immunogen:
Ile523-Asp760 (Accession Q12884), with N-terminal His Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
FAP
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
170 kDa melanoma membrane-bound gelatinase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE; Dipeptidyl peptidase FAP; DPPIV; Fap; FAPA; FAPalpha; fibroblast activation protein; fibroblast activation protein alpha; fibroblast activation protein, alpha; gelatine degradation protease FAP; Integral membrane serine protease; post-proline cleaving enzyme; Prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; Surface-expressed protease
Gene Symbols:
FAP
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Complement C5a
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01031
Gene ID (Entrez): 727
Immunogen: Thr678-Arg751, with N-terminal GST Tag
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: C5
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias: anaphylatoxin; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C4B1; C4B12; C4B2; C4B3; C4B5; C4F; C5; C5a; C5a anaphylatoxin; C5b; C5D; CH; CO4; complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD3; CPAMD4; DADB-112B14.11; ECLZB; FLJ17816; FLJ17822; FLJ60561; Hc; He; Hemolytic complement; MGC142298; MGC164979; prepro-C5; RGD1561905
Gene Symbols: C5
Isotype: IgG2b κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Complement C5a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01031
Gene ID (Entrez):
727
Immunogen:
Thr678-Arg751, with N-terminal GST Tag
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
C5
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias:
anaphylatoxin; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C4B1; C4B12; C4B2; C4B3; C4B5; C4F; C5; C5a; C5a anaphylatoxin; C5b; C5D; CH; CO4; complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD3; CPAMD4; DADB-112B14.11; ECLZB; FLJ17816; FLJ17822; FLJ60561; Hc; He; Hemolytic complement; MGC142298; MGC164979; prepro-C5; RGD1561905
Gene Symbols:
C5
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Product Type:
Antibody