7240893

Azurocidin Monoclonal Antibody (D1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Azurocidin

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

AZAMP; AZU; AZU1; Azurocidin; azurocidin 1; CAP37; cationic antimicrobial protein 37; cationic antimicrobial protein CAP37; HBP; Heparin-binding protein; hHBP; HUMAZUR; NAZC; neutrophil azurocidin; pHBP

Gene Symbols

AZU1

Isotype

IgG1 κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

D1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P20160

Gene ID (Entrez)

566

Immunogen

Pro23-Gly247 (Accession P20160), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

AZU1

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Description

  • Azurocidin, also called heparin-binding protein (HBP), is an inactive homolog of serine proteinases residing in granulocytes
  • Initially it was thought to have only activity against gram-negative bacteria
  • Later it was also found to act against gram-positive bacteria and C
  • albicans
  • Azurocidin is considered a family member of polymorphonuclear leukocytes- derived antimicrobial proteins like defensins, LL-37 and lysozyme
  • Azurocidin has been recognized as a player in the activation and modulation of the immune response and may act to alarm the immune system
  • The cationic domain at one side of the protein is essential for its antimicrobial activity
  • It is stored in azurophil granules as well as secretory granules and as a result partly released at early stage of extravasation
  • Azurocidin is involved in chemotaxis and activation of monocytes, cytokine release and phagocytosis leading to more efficient bacterial clearance
  • The primary targeted environment of azurocidin are cells in the bloodstream, that is the endothelial lining, and the extravascular surroundings
  • The interaction of azurocidin with leucocytes is mediated via beta 2-intergrins
  • High plasma levels of azurocidin might help with the identification of patients which are at risk in developing sepsis.

Compare Similar Items

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Img

Fischer Scientific

7240893

Mouse Monoclonal Antibody...


Antigen:
Azurocidin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
AZAMP; AZU; AZU1; Azurocidin; azurocidin 1; CAP37; cationic antimicrobial protein 37; cationic antimicrobial protein CAP37; HBP; Heparin-binding protein; hHBP; HUMAZUR; NAZC; neutrophil azurocidin; pHBP

Gene Symbols:
AZU1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
D1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20160

Gene ID (Entrez):
566

Immunogen:
Pro23-Gly247 (Accession P20160), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
AZU1

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Fischer Scientific

7240894

Mouse Monoclonal Antibody...


Antigen:
Procollagen I N-Peptide

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
Procollagen I N

Gene Symbols:
COL1A1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
H20

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P02452, P02454

Gene ID (Entrez):
1277, 29393

Immunogen:
Gln23-Pro161+LEHHHHHH

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
COL1A1

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Fischer Scientific

7240896

Mouse Monoclonal Antibody...


Antigen:
KIM-1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols:
Havcr1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C2

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96D42

Gene ID (Entrez):
26762

Immunogen:
Ser21-Ala240 (Accession Q96D42), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
Havcr1

Img

Fischer Scientific

7240896

Mouse Monoclonal Antibody...


Antigen:
KIM-1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols:
Havcr1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C2

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96D42

Gene ID (Entrez):
26762

Immunogen:
Ser21-Ala240 (Accession Q96D42), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
Havcr1