7240990

Thioredoxin 1 Monoclonal Antibody (3#), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Thioredoxin 1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Gene Symbols

TXN

Isotype

IgG2a κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

3#

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P10599

Gene ID (Entrez)

7295

Immunogen

Met1-Val105 (Accession P10599), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

TXN

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Description

  • Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
  • Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
  • The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
  • Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
  • The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
  • Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
  • Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

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Img

Fischer Scientific

7240990

Mouse Monoclonal Antibody...


Antigen:
Thioredoxin 1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Gene Symbols:
TXN

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
3#

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10599

Gene ID (Entrez):
7295

Immunogen:
Met1-Val105 (Accession P10599), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
TXN

Img

Fischer Scientific

7240991

Mouse Monoclonal Antibody...


Antigen:
SIGLEC10

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
PRO940; sialic acid binding Ig like lectin 10; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Siglec; SIGLEC10; Siglec-10; Siglecg; siglec-like gene 2; siglec-like protein 2; SLG2; UNQ477/PRO940

Gene Symbols:
SIGLEC10

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96LC7

Gene ID (Entrez):
89790

Immunogen:
Met571-Gln697 (Accession Q96LC7), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
SIGLEC10

Img

Fischer Scientific

7240991

Mouse Monoclonal Antibody...


Antigen:
SIGLEC10

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
PRO940; sialic acid binding Ig like lectin 10; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Siglec; SIGLEC10; Siglec-10; Siglecg; siglec-like gene 2; siglec-like protein 2; SLG2; UNQ477/PRO940

Gene Symbols:
SIGLEC10

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96LC7

Gene ID (Entrez):
89790

Immunogen:
Met571-Gln697 (Accession Q96LC7), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
SIGLEC10

Img

Fischer Scientific

7240992

Mouse Monoclonal Antibody...


Antigen:
ALPL

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
Akp2; Akp-2; Alkaline phosphatase 2; alkaline phosphatase 2, liver; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase precursor (EC 3.1.3.2); alkaline phosphatase tissue non-specific isoform; alkaline phosphatase tissue non-specific isoform/TNS-AP; alkaline phosphatase, biomineralization associated; alkaline phosphatase, intestinal; alkaline phosphatase, liver/bone/kidney; alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphomonoesterase; ALPI; Alpl; APTNAP; AP-TNAP; FLJ40094; FLJ93059; glycerophosphatase; HOPS; IAP; intestinal alkaline phosphatase; intestinal-type alkaline phosphatase; Kasahara isozyme; liver/bone/kidney isozyme; liver/bone/kidney-type alkaline phosphatase; MGC161443; MGC167935; PHOA; tissue-nonspecific alkaline phosphatase; tissue-nonspecific alkaline phosphatase precursor; tissue-nonspecific ALP; Tissue-nonspecific ALP alkaline phosphatase; TNAP; TNSALP; TNS-AP

Gene Symbols:
ALPL

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
D1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P05186

Gene ID (Entrez):
249

Immunogen:
Leu18-Arg335 (Accession P05186), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
ALPL