7240993

STING Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

STING

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q86WV6

Gene ID (Entrez)

340061

Immunogen

Leu159-Pro373 (Accession Q86WV6), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

TMEM173

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173

Gene Symbols

TMEM173

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling
  • This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression
  • STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway
  • Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240993

Rabbit Polyclonal Antibody...


Antigen:
STING

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q86WV6

Gene ID (Entrez):
340061

Immunogen:
Leu159-Pro373 (Accession Q86WV6), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
TMEM173

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173

Gene Symbols:
TMEM173

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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Mouse Monoclonal Antibody...


Antigen:
DNASE1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P24855

Gene ID (Entrez):
1773

Immunogen:
Gly19-Ala259 (Accession P24855), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
DNASE1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease-1; DNase I; DNase I, lysosomal; DNASE1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I

Gene Symbols:
DNASE1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7240994

Mouse Monoclonal Antibody...


Antigen:
DNASE1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P24855

Gene ID (Entrez):
1773

Immunogen:
Gly19-Ala259 (Accession P24855), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
DNASE1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease-1; DNase I; DNase I, lysosomal; DNASE1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I

Gene Symbols:
DNASE1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7240994

Mouse Monoclonal Antibody...


Antigen:
DNASE1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P24855

Gene ID (Entrez):
1773

Immunogen:
Gly19-Ala259 (Accession P24855), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
DNASE1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease-1; DNase I; DNase I, lysosomal; DNASE1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I

Gene Symbols:
DNASE1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody