7241346

iNOS Monoclonal Antibody (CXNFT), Brilliant Violet™ 421, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

iNOS

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols

Nos2

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Nos2

Clone

CXNFT

Applications

Flow Cytometry

Conjugate

Brilliant Violet 421

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P29477

Gene ID (Entrez)

18126

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

7241557

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7241415

Rat Monoclonal Antibody...

Img

Fischer Scientific

7241340

Armenian Hamster Monoclonal Antibod...

Img

Fischer Scientific

7241327

Rat Monoclonal Antibody...

Img

Fischer Scientific

7247228

Rabbit Monoclonal Antibody...

Img

Fischer Scientific

7241395

Rat Monoclonal Antibody...

Img

Fischer Scientific

7247265

Rabbit Monoclonal Antibody...

Img

Fischer Scientific

7247265

Rabbit Monoclonal Antibody...

Description

  • iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
  • Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
  • NO production is mediated by members of the nitric oxide synthase (NOS) family
  • iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
  • NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
  • Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
  • All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
  • iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
  • Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
  • Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
  • After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
  • Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
  • Diseases associated with iNOS dysfunction include achalasia and impotence.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7241346

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Nos2

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7241348

Rat Monoclonal Antibody...


Antigen:
CD366 (TIM3)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3

Gene Symbols:
Havcr2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Havcr2

Clone:
RMT3-23

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q8VIM0

Gene ID (Entrez):
171285

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7241349

Rat Monoclonal Antibody...


Antigen:
Ki-67

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Gene Symbols:
Mki67

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Mki67

Clone:
SolA15

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 480

Host Species:
Rat

Target Species:
Canine, Cynomolgus Monkey, Human, Mouse, Non-human Primate, Rat

Gene Accession No.:
E9PVX6, P46013

Gene ID (Entrez):
100686578, 102135895, 17345, 291234, 4288

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7241351

Rat Monoclonal Antibody...


Antigen:
Ki-67

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Gene Symbols:
Mki67

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Mki67

Clone:
SolA15

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Target Species:
Canine, Cynomolgus Monkey, Human, Mouse, Non-human Primate, Rat

Gene Accession No.:
E9PVX6, P46013

Gene ID (Entrez):
100686578, 102135895, 17345, 291234, 4288

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody