7244944
PD-L1 Fc Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PD-L1 Fc
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q9NZQ7
Gene ID (Entrez)
29126
Immunogen
CHO cells-derived Recombinant Human PD-L1 Fc
Purification Method
Antigen affinity chromatography
Gene
Cd274
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols
Cd274
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: FTVTVPKDLY VVEYGSNMTI ECKFPVEKQL DLAALIVYWE MEDKNIIQFV HGEEDLKVQH SSYRQRARLL KDQLSLGNAA LQITDVKLQD AGVYRCMISY GGADYKRITV KVNAPYNKIN QRILVVDPVT SEHELTCQAE GYPKAEVIWT SSDHQVLSGK TTTTNSKREE KLFNVTSTLR INTTTNEIFY CTFRRLDPEE NHTAELVIPE LPLAHPPNER GGPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human PD-L1 Fc
- Anti-Human PD-L1 Fc-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human PD-L1 Fc by sandwich ELISA (using 100 μL/well), a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human PD-L1 Fc (500-P321) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human PD-L1 Fc
- Western Blot: To detect Human PD-L1 Fc by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible development reagents, the detection limit for Recombinant Human PD-L1 Fc is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P321BT-1MG will be provided as 2 x 500 μg Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member
- To date, one specific receptor has been identified that can be ligated by PD-L1
- This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling
- Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production
- PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation
- Thus, PD-L1 might play an important role in tumor immune evasion.
Compare Similar Items
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Antigen: PD-L1 Fc
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9NZQ7
Gene ID (Entrez): 29126
Immunogen: CHO cells-derived Recombinant Human PD-L1 Fc
Purification Method: Antigen affinity chromatography
Gene: Cd274
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols: Cd274
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
PD-L1 Fc
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9NZQ7
Gene ID (Entrez):
29126
Immunogen:
CHO cells-derived Recombinant Human PD-L1 Fc
Purification Method:
Antigen affinity chromatography
Gene:
Cd274
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols:
Cd274
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Uteroglobin
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P11684
Gene ID (Entrez): 7356
Immunogen: E.coli-derived Recombinant Human Uteroglobin
Purification Method: Antigen affinity chromatography
Gene: SCGB1A1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg
Gene Symbols: SCGB1A1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Uteroglobin
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P11684
Gene ID (Entrez):
7356
Immunogen:
E.coli-derived Recombinant Human Uteroglobin
Purification Method:
Antigen affinity chromatography
Gene:
SCGB1A1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg
Gene Symbols:
SCGB1A1
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CXCL6
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method: Antigen affinity chromatography
Gene: __
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CXCL6
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method:
Antigen affinity chromatography
Gene:
__
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IL-6
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P20607
Gene ID (Entrez): 24498
Immunogen: E.coli-derived Recombinant Rat IL-6
Purification Method: Antigen affinity chromatography
Gene: Il6
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Gene Symbols: Il6
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-6
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P20607
Gene ID (Entrez):
24498
Immunogen:
E.coli-derived Recombinant Rat IL-6
Purification Method:
Antigen affinity chromatography
Gene:
Il6
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Gene Symbols:
Il6
Primary or Secondary:
Primary
Content And Storage:
-20°C