7244998

Neurturin Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Neurturin

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q99748

Gene ID (Entrez)

4902

Immunogen

E.coli-derived Recombinant Human Neurturin

Purification Method

Antigen affinity chromatography

Gene

NRTN

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

neurturin; NRTN; NTN; prepro-neurturin

Gene Symbols

NRTN

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: ARLGARPCGL RELEVRVSEL GLGYASDETV LFRYCAGACE AAARVYDLGL RRLRQRRRLR RERVRAQPCC RPTAYEDEVS FLDAHSRYHT VHELSARECA CV
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Neurturin
  • Anti-Human Neurturin-specific antibody was purified by affinity chromatography employing an immobilized Human Neurturin matrix
  • Sandwich ELISA: To detect Human Neurturin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human Neurturin (500-P102Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Neurturin
  • Western Blot: To detect Human Neurturin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Neurturin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation
  • A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin
  • Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha
  • The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently and termed GDNFR-b, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFR-a-2 recently
  • NTN binds to and forms a complex with GFR-a-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway
  • Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations
  • Neurturin and GDNF define a new family of neurotrophic factors.

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Fischer Scientific

7244998

Rabbit Polyclonal Antibody...


Antigen:
Neurturin

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q99748

Gene ID (Entrez):
4902

Immunogen:
E.coli-derived Recombinant Human Neurturin

Purification Method:
Antigen affinity chromatography

Gene:
NRTN

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
neurturin; NRTN; NTN; prepro-neurturin

Gene Symbols:
NRTN

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245000

Mouse Monoclonal Antibody...


Antigen:
E. coli serotype O

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
E. coli serotypes: O18, O44, O112, O125.

Purification Method:
Protein G

Gene:
__

Concentration:
1.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
Escherichia coli

Gene Symbols:
__

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Antigen:
GDF3

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9NR23

Gene ID (Entrez):
9573

Immunogen:
E.coli-derived Recombinant Human GDF-3

Purification Method:
Antigen affinity chromatography

Gene:
GDF3

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C78318; ecat9; Gdf3; Gdf-3; growth differentiation factor 3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6; RGD1564178; UNQ222/PRO248; VG-1-related protein 2; Vgr2; Vgr-2

Gene Symbols:
GDF3

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
GDF3

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9NR23

Gene ID (Entrez):
9573

Immunogen:
E.coli-derived Recombinant Human GDF-3

Purification Method:
Antigen affinity chromatography

Gene:
GDF3

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C78318; ecat9; Gdf3; Gdf-3; growth differentiation factor 3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6; RGD1564178; UNQ222/PRO248; VG-1-related protein 2; Vgr2; Vgr-2

Gene Symbols:
GDF3

Primary or Secondary:
Primary

Content And Storage:
-20°C