7245122
CD22 (soluble) Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD22 (soluble)
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P20273
Gene ID (Entrez)
933
Immunogen
CHO cells-derived Recombinant Human sCD22
Purification Method
Antigen affinity chromatography
Gene
CD22
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Gene Symbols
CD22
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Seq
- of rec
- protein: SKWVFEHPET LYAWEGACVW IPCTYRALDG DLESFILFHN PEYNKNTSKF DGTRLYESTK DGKVPSEQKR VQFLGDKNKN CTLSIHPVHL NDSGQLGLRM ESKTEKWMER IHLNVSERPF PPHIQLPPEI QESQEVTLTC LLNFSCYGYP IQLQWLLEGV PMRQAAVTST SLTIKSVFTR SELKFSPQWS HHGKIVTCQL QDADGKFLSN DTVQLNVKHT PKLEIKVTPS DAIVREGDSV TMTCEVSSSN PEYTTVSWLK DGTSLKKQNT FTLNLREVTK DQSGKYCCQV SNDVGPGRSE EVFLQVQYAP EPSTVQILHS PAVEGSQVEF LCMSLANPLP TNYTWYHNGK EMQGRTEEKV HIPKILPWHA GTYSCVAENI LGTGQRGPGA ELDVQYPPKK VTTVIQNPMP IREGDTVTLS CNYNSSNPSV TRYEWKPHGA WEEPSLGVLK IQNVGWDNTT IACARCNSWC SWASPVALNV QYAPRDVRVR KIKPLSEIHS GNSVSLQCDF SSSHPKEVQF FWEKNGRLLG KESQLNFDSI SPEDAGSYSC WVNNSIGQTA SKAWTLEVLY APRRLRVSMS PGDQVMEGKS ATLTCESDAN PPVSHYTWFD WNNQSLPHHS QKLRLEPVKV QHSGAYWCQG TNSVGKGRSP LSTLTVYYSP ETIGRR
- Sandwich ELISA: To detect Hu sCD22 by sandwich ELISA (using 100 uL/well antibody solution) a conc
- of 0.5-2.0 ug/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Hu sCD22 (500-P227Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of rec
- Hu sCD22
- WB: To detect Hu sCD22 by WB analysis this antibody can be used at a conc
- of 0.1-0.2 ug/mL
- Used in conjunction with compatible secondary reagents the detection limit for rec
- Hu sCD22 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
- CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
- CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
- Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 preferentially binds to alpha2,6-linked sialic acid
- The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
- Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
- CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.
Compare Similar Items
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Antigen: CD22 (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20273
Gene ID (Entrez): 933
Immunogen: CHO cells-derived Recombinant Human sCD22
Purification Method: Antigen affinity chromatography
Gene: CD22
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Gene Symbols: CD22
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CD22 (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20273
Gene ID (Entrez):
933
Immunogen:
CHO cells-derived Recombinant Human sCD22
Purification Method:
Antigen affinity chromatography
Gene:
CD22
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Gene Symbols:
CD22
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CCL6
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P27784
Gene ID (Entrez): 20305
Immunogen: E.coli-derived Recombinant Murine C10 (CCL6)
Purification Method: Antigen affinity chromatography
Gene: Ccl6
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: c10; CC chemokine C10; C-C motif chemokine 6; Ccl6; CCL6(22-95); CCL6(23-95); chemokine (C-C motif) ligand 6; chemokine ligand 6; Mrp-1; Protein C10; Scay6; Scya6; small inducible cytokine A6; small-inducible cytokine A6
Gene Symbols: Ccl6
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CCL6
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P27784
Gene ID (Entrez):
20305
Immunogen:
E.coli-derived Recombinant Murine C10 (CCL6)
Purification Method:
Antigen affinity chromatography
Gene:
Ccl6
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
c10; CC chemokine C10; C-C motif chemokine 6; Ccl6; CCL6(22-95); CCL6(23-95); chemokine (C-C motif) ligand 6; chemokine ligand 6; Mrp-1; Protein C10; Scay6; Scya6; small inducible cytokine A6; small-inducible cytokine A6
Gene Symbols:
Ccl6
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Maspin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P36952
Gene ID (Entrez): 5268
Immunogen: E.coli-derived Recombinant Human Maspin
Purification Method: Antigen affinity chromatography
Gene: SERPINB5
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 1110036M19Rik; AI462524; AI646751; Maspin; ovalbumin; peptidase inhibitor 5; PI5; PI-5; protease inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) peptidase inhibitor, clade B, member 5; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serine (or cysteine) proteinase inhibitor, clade B, member 5; serine protease inhibitor 7; serpin B5; serpin family B member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5; Spi5; Spi7
Gene Symbols: SERPINB5
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Maspin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P36952
Gene ID (Entrez):
5268
Immunogen:
E.coli-derived Recombinant Human Maspin
Purification Method:
Antigen affinity chromatography
Gene:
SERPINB5
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
1110036M19Rik; AI462524; AI646751; Maspin; ovalbumin; peptidase inhibitor 5; PI5; PI-5; protease inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) peptidase inhibitor, clade B, member 5; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serine (or cysteine) proteinase inhibitor, clade B, member 5; serine protease inhibitor 7; serpin B5; serpin family B member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5; Spi5; Spi7
Gene Symbols:
SERPINB5
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CCL1
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P22362
Gene ID (Entrez): 6346
Immunogen: E.coli-derived Recombinant Human I-309 (CCL1)
Purification Method: Antigen affinity chromatography
Gene: CCL1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: BF534335; C-C motif chemokine 1; C-C motif chemokine ligand 1; CCL 1; Ccl1; CCR8 ligand; chemokine (C-C motif) ligand 1; I-309; inflammatory cytokine I-309; P500; SCYA1; SISe; SIS-epsilon; small inducible cytokine A1; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); small-inducible cytokine A1; T lymphocyte-secreted protein I-309; TCA3; TCA-3; T-cell activation protein 3
Gene Symbols: CCL1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CCL1
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P22362
Gene ID (Entrez):
6346
Immunogen:
E.coli-derived Recombinant Human I-309 (CCL1)
Purification Method:
Antigen affinity chromatography
Gene:
CCL1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
BF534335; C-C motif chemokine 1; C-C motif chemokine ligand 1; CCL 1; Ccl1; CCR8 ligand; chemokine (C-C motif) ligand 1; I-309; inflammatory cytokine I-309; P500; SCYA1; SISe; SIS-epsilon; small inducible cytokine A1; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); small-inducible cytokine A1; T lymphocyte-secreted protein I-309; TCA3; TCA-3; T-cell activation protein 3
Gene Symbols:
CCL1
Primary or Secondary:
Primary
Content And Storage:
-20°C