7245153

CXCL13 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CXCL13

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

O43927

Gene ID (Entrez)

10563

Immunogen

E.coli-derived Recombinant Human BCA-1 (CXCL13)

Purification Method

Antigen affinity chromatography

Gene

Cxcl13

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

4631412M08Rik; Angie; ANGIE2; B cell-attracting chemokine 1; b lymphocyte chemoattractant; BCA1; BCA-1; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); BLC; BLR1L; B-lymphocyte chemoattractant; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chem; chemokine (C-X-C motif) ligand 13; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); CXC; CXC chemokine BLC; CXC motif chemokine; CXC motif chemokine 13; C-X-C motif chemokine 13; C-X-C motif chemokine ligand 13; CXCL; Cxcl13; SCYB13; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13

Gene Symbols

Cxcl13

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human BCA-1 (CXCL13)
  • Anti-Human BCA-1 (CXCL13)-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human BCA-1 (CXCL13) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human BCA-1 (CXCL13) (500-P141) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human BCA-1 (CXCL13)
  • Western Blot: To detect hBCA-1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hBCA-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P141BT-1MG will be provided as 2 x 500 μg CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in the secondary lymphoid organs
  • It preferentially promotes the migration of B lymphocytes (both B-1 and B-2) to the follicles of the spleen, lymph nodes, and Peyer's patches
  • It is produced by macrophages, and in mouse the highest constitutive producers include large peritoneal macrophages, Kuppfer cells and lung macrophages (both CD11c+ and CD11c-)
  • The cellular ligand for CXCL13 is CXCR5 also known as BLR-1 (Burkitt’s Lymphoma Receptor 1)
  • CXCR5 is expressed on B cells, Tfh cells and, to a lower degree, some memory T cell populations
  • CXCL13 plays an important role in the development of chronic lymphocytic leukemia (CCL)
  • CXCL13 is also a plasma biomarker for germinal center activity and generation of broadly neutralizing antibodies against HIV.

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7245153

Rabbit Polyclonal Antibody...


Antigen:
CXCL13

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O43927

Gene ID (Entrez):
10563

Immunogen:
E.coli-derived Recombinant Human BCA-1 (CXCL13)

Purification Method:
Antigen affinity chromatography

Gene:
Cxcl13

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
4631412M08Rik; Angie; ANGIE2; B cell-attracting chemokine 1; b lymphocyte chemoattractant; BCA1; BCA-1; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); BLC; BLR1L; B-lymphocyte chemoattractant; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chem; chemokine (C-X-C motif) ligand 13; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); CXC; CXC chemokine BLC; CXC motif chemokine; CXC motif chemokine 13; C-X-C motif chemokine 13; C-X-C motif chemokine ligand 13; CXCL; Cxcl13; SCYB13; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13

Gene Symbols:
Cxcl13

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Applications:
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Conjugate:
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Host Species:
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Target Species:
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Gene Accession No.:
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Gene ID (Entrez):
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Immunogen:
UV-inactivated Staphylococcus aureus cells.

Purification Method:
Protein A

Gene:
__

Concentration:
3.1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
MRSA; s aureus; S. aureus; staphylococcus aureus methicillin-resistant

Gene Symbols:
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Primary or Secondary:
Primary

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Applications:
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Conjugate:
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Host Species:
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Target Species:
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Gene ID (Entrez):
19264

Immunogen:
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Purification Method:
Affinity chromatography

Gene:
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Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
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Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Gene Symbols:
Ptprc

Primary or Secondary:
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Applications:
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Conjugate:
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Host Species:
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Target Species:
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Gene Accession No.:
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Gene ID (Entrez):
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Immunogen:
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Purification Method:
Protein G

Gene:
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Concentration:
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Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
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Gene Symbols:
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Primary or Secondary:
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Content And Storage:
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