7245167

IGFBP5 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IGFBP5

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P24593

Gene ID (Entrez)

3488

Immunogen

E.coli-derived Recombinant Human IGF-BP5

Purification Method

Antigen affinity chromatography

Gene

IGFBP5

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI256729; AW208790; IBP 5; IBP5; IBP-5; IGF BP5; IGF-binding protein 5; IGFBP; IGFBP 5; Igfbp5; IGF-BP5; Igfbp-5; IGFBP-5P; Insulin like growth factor binding protein; insulin like growth factor binding protein 5; insulin-like growth factor binding protein 5; insulin-like growth factor binding protein-5; insulin-like growth factor-binding protein 5

Gene Symbols

IGFBP5

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP5
  • Anti-Human IGF-BP5-specific antibody was purified by affinity chromatography employing an immobilized Human IGF-BP5 matrix
  • Sandwich ELISA: To detect Human IGF-BP5 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IGF-BP5 (500-P232Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-BP5
  • Western Blot: To detect Human IGF-BP5 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IGF-BP5 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • The insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs
  • They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system
  • Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment
  • In addition, the IGFBPs appear to have biological activity independent of the IGFs
  • Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors
  • For instance, IGFBP1 is negatively regulated by insulin production
  • The IGFBP1 gene is expressed at a high level during fetal liver development and in response to nutritional changes and diabetes
  • It has been suggested that IGFBP2 functions as chaperone, escorting IGFs to their target tissues
  • It is expressed in several human tissues including fetal eye and fetal brain
  • IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs
  • Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury
  • IGFBP5 is secreted by myoblasts and may play a key role in muscle differentiation.

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Show Difference

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Fischer Scientific

7245167

Rabbit Polyclonal Antibody...


Antigen:
IGFBP5

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P24593

Gene ID (Entrez):
3488

Immunogen:
E.coli-derived Recombinant Human IGF-BP5

Purification Method:
Antigen affinity chromatography

Gene:
IGFBP5

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI256729; AW208790; IBP 5; IBP5; IBP-5; IGF BP5; IGF-binding protein 5; IGFBP; IGFBP 5; Igfbp5; IGF-BP5; Igfbp-5; IGFBP-5P; Insulin like growth factor binding protein; insulin like growth factor binding protein 5; insulin-like growth factor binding protein 5; insulin-like growth factor binding protein-5; insulin-like growth factor-binding protein 5

Gene Symbols:
IGFBP5

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245170

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Antigen:
IGFBP3

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P17936

Gene ID (Entrez):
3486

Immunogen:
E.coli-derived Recombinant Human IGF-BP3

Purification Method:
Antigen affinity chromatography

Gene:
IGFBP3

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703

Gene Symbols:
IGFBP3

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245170

Rabbit Polyclonal Antibody...


Antigen:
IGFBP3

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P17936

Gene ID (Entrez):
3486

Immunogen:
E.coli-derived Recombinant Human IGF-BP3

Purification Method:
Antigen affinity chromatography

Gene:
IGFBP3

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703

Gene Symbols:
IGFBP3

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245172

Rabbit Polyclonal Antibody...


Antigen:
IGFBP3

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P17936

Gene ID (Entrez):
3486

Immunogen:
E.coli-derived Recombinant Human IGF-BP3

Purification Method:
Antigen affinity chromatography

Gene:
IGFBP3

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703

Gene Symbols:
IGFBP3

Primary or Secondary:
Primary

Content And Storage:
-20°C