7245226

IL4R (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL4R (soluble)

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P24394

Gene ID (Entrez)

3566

Immunogen

CHO cells-derived Recombinant Human IL-4 Receptor alpha

Purification Method

Antigen affinity chromatography

Gene

IL4R

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha

Gene Symbols

IL4R

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: GNMKVLQEPT CVSDYMSIST CEWKMNGPTN CSTELRLLYQ LVFLLSEAHT CIPENNGGAG CVCHLLMDDV VSADNYTLDL WAGQQLLWKG SFKPSEHVKP RAPGNLTVHT NVSDTLLLTW SNPYPPDNYL YNHLTYAVNI WSENDPADFR IYNVTYLEPS LRIAASTLKS GISYRARVRA WAQCYNTTWS EWSPSTKWHN SYREPFEQH
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sIL-4 Receptor alpha
  • Anti-Human sIL-4 Receptor alpha-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human sIL-4 Receptor alpha by sandwich ELISA (using 100 μL/well), a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sIL-4 Receptor alpha (500-P325) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human sIL-4 Receptor alpha
  • Western Blot: To detect Human sIL-4 Receptor alpha by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible development reagents, the detection limit for Recombinant Human sIL-4 Receptor alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P325BT-1MG will be provided as 2 x 500 μg IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation
  • The IL4 response is involved in promoting Th2 differentiation
  • The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells
  • It has no signaling abilities
  • Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.

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7245226

Rabbit Polyclonal Antibody...


Antigen:
IL4R (soluble)

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P24394

Gene ID (Entrez):
3566

Immunogen:
CHO cells-derived Recombinant Human IL-4 Receptor alpha

Purification Method:
Antigen affinity chromatography

Gene:
IL4R

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha

Gene Symbols:
IL4R

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Mouse Monoclonal Antibody...


Antigen:
Neutrophil elastase

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P08246

Gene ID (Entrez):
1991

Immunogen:
Purified human Neutrophil Elastase.

Purification Method:
Protein A

Gene:
ELANE

Concentration:
1.8 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease

Gene Symbols:
ELANE

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Antigen:
Neutrophil elastase

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P08246

Gene ID (Entrez):
1991

Immunogen:
Purified human Neutrophil Elastase.

Purification Method:
Protein A

Gene:
ELANE

Concentration:
1.8 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease

Gene Symbols:
ELANE

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Antigen:
MCP-5

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q62401

Gene ID (Entrez):
20293

Immunogen:
E.coli-derived Recombinant Murine MCP-5 (CCL12)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl12

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C-C motif chemokine 12; Ccl12; chemokine (C-C motif) ligand 12; MCP-1-related chemokine; Mcp5; MCP-5; Monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya12; small inducible cytokine A12; small-inducible cytokine A12

Gene Symbols:
Ccl12

Primary or Secondary:
Primary

Content And Storage:
-20°C