7245310

IL-4 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-4

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P05112

Gene ID (Entrez)

3565

Immunogen

E.coli-derived Recombinant Human IL-4

Purification Method

Antigen affinity chromatography

Gene

Il4

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Gene Symbols

Il4

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-4
  • Anti-Human IL-4-specific antibody was purified by affinity chromatography employing an immobilized Human IL-4 matrix
  • Sandwich ELISA: To detect Human IL-4 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IL-4 (500-P24Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IL-4
  • Western Blot: To detect Human IL-4 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IL-4 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor
  • IL-4 has been found to have the broadest range of actions
  • The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13
  • STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4
  • The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q
  • In particular, IL-4 is located in close proximity to IL13 on the chromosome
  • Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome
  • IL-4 delta 2 is a known splice variant of IL-4.

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7245310

Rabbit Polyclonal Antibody...


Antigen:
IL-4

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P05112

Gene ID (Entrez):
3565

Immunogen:
E.coli-derived Recombinant Human IL-4

Purification Method:
Antigen affinity chromatography

Gene:
Il4

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Gene Symbols:
Il4

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Midkine

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P21741

Gene ID (Entrez):
4192

Immunogen:
E.coli-derived Recombinant Human Midkine

Purification Method:
Antigen affinity chromatography

Gene:
Mdk

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
amphiregulin-associated protein; ARAP; FLJ27379; MDK; Mek; Midgestation and kidney protein; midkine; midkine (neurite growth-promoting factor 2); MK; MK1; NEGF2; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; Retanoic acid-responsive protein; retinoic acid inducible factor; retinoic acid-induced differentiation factor; retinoic acid-responsive protein

Gene Symbols:
Mdk

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
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Applications:
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Conjugate:
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Host Species:
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Target Species:
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Gene Accession No.:
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Gene ID (Entrez):
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Immunogen:
Valproic acid, conjugated to KLH.

Purification Method:
Protein A

Gene:
__

Concentration:
1.0 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
C8H16O2; Depakene; Depakine; Dipropylacetic acid

Gene Symbols:
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Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Antigen:
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Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01579

Gene ID (Entrez):
3458

Immunogen:
E.coli-derived Recombinant Human IFN-gamma

Purification Method:
Antigen affinity chromatography

Gene:
IFNG

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Gene Symbols:
IFNG

Primary or Secondary:
Primary

Content And Storage:
-20°C