7245328
SCF Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SCF
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P21583
Gene ID (Entrez)
4254
Immunogen
E.coli-derived Recombinant Human SCF
Purification Method
Antigen affinity chromatography
Gene
KITLG
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols
KITLG
Primary or Secondary
Primary
Content And Storage
-20°C
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Description
- AA Sequence of recombinant protein: MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human SCF
- Anti-Human SCF-specific antibody was purified by affinity chromatography employing an immobilized Human SCF matrix
- Sandwich ELISA: To detect Human SCF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human SCF (500-P48Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human SCF
- Western Blot: To detect hSCF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hSCF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways
- Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways
- SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines
- The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma
- At least two isoforms of SCF are known to exist.
Compare Similar Items
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Antigen: SCF
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P21583
Gene ID (Entrez): 4254
Immunogen: E.coli-derived Recombinant Human SCF
Purification Method: Antigen affinity chromatography
Gene: KITLG
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols: KITLG
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
SCF
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P21583
Gene ID (Entrez):
4254
Immunogen:
E.coli-derived Recombinant Human SCF
Purification Method:
Antigen affinity chromatography
Gene:
KITLG
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols:
KITLG
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: TNF alpha
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: P01375
Gene ID (Entrez): 7124
Immunogen: E.coli-derived Recombinant Human TNF-alpha
Purification Method: Antigen affinity chromatography
Gene: Tnf
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols: Tnf
Primary or Secondary: __
Content And Storage: -20°C
Antigen:
TNF alpha
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P01375
Gene ID (Entrez):
7124
Immunogen:
E.coli-derived Recombinant Human TNF-alpha
Purification Method:
Antigen affinity chromatography
Gene:
Tnf
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols:
Tnf
Primary or Secondary:
__
Content And Storage:
-20°C
Antigen: G-CSF
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P09920
Gene ID (Entrez): 12985
Immunogen: E.coli-derived Recombinant Murine G-CSF
Purification Method: Antigen affinity chromatography
Gene: Csf3
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C17orf33; colony stimulating factor 3; colony stimulating factor 3 (granulocyte); CSF 3; CSF3; CSF3OS; Csfg; filgrastim; GCSF; G-CSF; Granulocyte colony-stimulating factor; granulocyte-colony stimulating factor; gsf3; lenograstim; MGC45931; MGI-IG; Pluripoietin; RP23-395E10.4
Gene Symbols: Csf3
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
G-CSF
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P09920
Gene ID (Entrez):
12985
Immunogen:
E.coli-derived Recombinant Murine G-CSF
Purification Method:
Antigen affinity chromatography
Gene:
Csf3
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C17orf33; colony stimulating factor 3; colony stimulating factor 3 (granulocyte); CSF 3; CSF3; CSF3OS; Csfg; filgrastim; GCSF; G-CSF; Granulocyte colony-stimulating factor; granulocyte-colony stimulating factor; gsf3; lenograstim; MGC45931; MGI-IG; Pluripoietin; RP23-395E10.4
Gene Symbols:
Csf3
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Factor VIII
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P00451
Gene ID (Entrez): 2157
Immunogen: Purified human Factor VIII.
Purification Method: Protein A
Gene: F8
Concentration: 1.1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols: F8
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Factor VIII
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P00451
Gene ID (Entrez):
2157
Immunogen:
Purified human Factor VIII.
Purification Method:
Protein A
Gene:
F8
Concentration:
1.1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols:
F8
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles