7245412

MIA Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MIA

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q16674

Gene ID (Entrez)

8190

Immunogen

E.coli-derived Recombinant Human MIA

Purification Method

Antigen affinity chromatography

Gene

MIA

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

cartilage derived retinoic acid sensitive protein; cartilage-derived retinoic acid-sensitive protein; Cdrap; CD-RAP; melanoma inhibitory activity; melanoma inhibitory activity 1; melanoma inhibitory activity protein; melanoma inhibitory activity/condrocyte-derived retinoic acid sensitive protein homolog (MIA/CD-RAP); melanoma-derived growth regulatory protein; melanoma-inhibitory-activity; MIA; Mia1

Gene Symbols

MIA

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MGPMPKLADR KLCADQECSH PISMAVALQD YMAPDCRFLT IHRGQVVYVF SKLKGRGRLF WGGSVQGDYY GDLAARLGYF PSSIVREDQT LKPGKVDVKT DKWDFYCQ
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MIA
  • Anti-Human MIA-specific antibody was purified by affinity chromatography employing an immobilized Human MIA matrix
  • Sandwich ELISA: To detect Human MIA by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human MIA (500-P243Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human MIA
  • Western Blot: To detect Human MIA by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human MIA is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • Tumorigenesis is a process that is mediated by a network of membrane, cytosolic and nuclear associated factors, which regulate proliferation and cell-matrix interaction through signaling cascades
  • The phenotype of malignant melanomas in vivo depends on the global expression of stimulatory or inhibitory factors generated in both the tumors cells and their environment
  • One example, Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP), MIA) is a Src homology 3 (SH3)-like domain containing protein that is secreted from chondrocytes and malignant melanoma cells
  • MIA is translated as a 131-amino acid pro-form and processed into a mature 107-amino acid protein after cleavage of a secretion signal
  • MIA is expressed during chondrogenesis and in mature chondrocytes, suggesting that MIA is necessary for normal cartilage cell phenotype
  • MIA mRNA is present in carcinomas of the colon, ovary, kidney, and head/neck, and may represent a marker to monitor melanomic activity.

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7245412

Rabbit Polyclonal Antibody...


Antigen:
MIA

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q16674

Gene ID (Entrez):
8190

Immunogen:
E.coli-derived Recombinant Human MIA

Purification Method:
Antigen affinity chromatography

Gene:
MIA

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
cartilage derived retinoic acid sensitive protein; cartilage-derived retinoic acid-sensitive protein; Cdrap; CD-RAP; melanoma inhibitory activity; melanoma inhibitory activity 1; melanoma inhibitory activity protein; melanoma inhibitory activity/condrocyte-derived retinoic acid sensitive protein homolog (MIA/CD-RAP); melanoma-derived growth regulatory protein; melanoma-inhibitory-activity; MIA; Mia1

Gene Symbols:
MIA

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245415

Rabbit Polyclonal Antibody...


Antigen:
IL-4

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P07750

Gene ID (Entrez):
16189

Immunogen:
E.coli-derived Recombinant Murine IL-4

Purification Method:
Antigen affinity chromatography

Gene:
Il4

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Gene Symbols:
Il4

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245417

Mouse Monoclonal Antibody...


Antigen:
GnRH1

Applications:
ELISA, Immunohistochemistry, Radioimmune Assays (RIA)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01148

Gene ID (Entrez):
2796

Immunogen:
Purified human gonadotropin releasing hormone.

Purification Method:
Protein G

Gene:
GNRH1

Concentration:
0.8 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1

Gene Symbols:
GNRH1

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Rabbit Polyclonal Antibody...


Antigen:
IGFBP7

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q16270

Gene ID (Entrez):
3490

Immunogen:
E.coli-derived Recombinant Human IGF-BP7

Purification Method:
Antigen affinity chromatography

Gene:
IGFBP7

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor

Gene Symbols:
IGFBP7

Primary or Secondary:
Primary

Content And Storage:
-20°C