7245582
CD45R (B220) Monoclonal Antibody (RA3-6B2), Brilliant Violet™ 650, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD45R (B220)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols
PTPRC
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Clone
RA3-6B2
Applications
Flow Cytometry
Conjugate
Brilliant Violet 650
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P06800, P08575
Gene ID (Entrez)
19264, 5788
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
PTPRC
Related Products
Description
- CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
- CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
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Antigen: CD45R (B220)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols: PTPRC
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: RA3-6B2
Applications: Flow Cytometry
Conjugate: Brilliant Violet 650
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P06800, P08575
Gene ID (Entrez): 19264, 5788
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: PTPRC
Antigen:
CD45R (B220)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols:
PTPRC
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
RA3-6B2
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 650
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P06800, P08575
Gene ID (Entrez):
19264, 5788
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
PTPRC
Antigen: Factor VIII
Concentration: 0.9 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols: F8
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Clone: F8C-27.4
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P00451
Gene ID (Entrez): 2157
Isotype: IgG2a
Purification Method: Protein G
Gene: F8
Antigen:
Factor VIII
Concentration:
0.9 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols:
F8
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Clone:
F8C-27.4
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P00451
Gene ID (Entrez):
2157
Isotype:
IgG2a
Purification Method:
Protein G
Gene:
F8
Antigen: Streptococcus Group A
Concentration: 1.56 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Clone: HSA12-340.5
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG2a
Purification Method: Protein A
Gene: __
Antigen:
Streptococcus Group A
Concentration:
1.56 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Clone:
HSA12-340.5
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG2a
Purification Method:
Protein A
Gene:
__
Antigen: Streptococcus Group A
Concentration: 1.56 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Clone: HSA12-340.5
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG2a
Purification Method: Protein A
Gene: __
Antigen:
Streptococcus Group A
Concentration:
1.56 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Clone:
HSA12-340.5
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG2a
Purification Method:
Protein A
Gene:
__