89-000-803
mitogen-activated protein kinase kinase kinase 4, Mouse, Clone: 4F10, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-000-803-Each-of-1 | In Stock | ₹ 43,892.28 |
89-000-803 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,892.28
GST (18%): ₹ 7,900.61
Total Price: ₹ 51,792.89
Antigen
mitogen-activated protein kinase kinase kinase 4
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_005922
Gene Symbols
MAP3K4
Immunogen
MAP3K4 (NP_005913, 1201 a.a. ∼ 1300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Research Discipline
Kinases
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Clone
4F10
Description
Mouse monoclonal antibody raised against a partial recombinant MAP3K4.
Gene
MAP3K4
Gene Alias
FLJ42439/KIAA0213/MAPKKK4/MEKK4/MTK1/PRO0412
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Whole Molecule
Yes
Gene ID (Entrez)
4216
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Related Products
Description
- The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK
- While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors
- This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1
- This protein contains a protein kinase catalytic domain at the C terminus
- The N-terminal nonkinase domain may contain a regulatory domain
- Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways, but not the ERK pathway
- In vitro kinase studies indicated that recombinant MEKK4 can specifically phosphorylate and activate PRKMK6 and SERK1, MAPKKs that activate CSBP2 and JNK, respectively but cannot phosphorylate PRKMK1, an MAPKK that activates ERKs
- MEKK4 is a major mediator of environmental stresses that activate the CSBP2 MAPK pathway, and a minor mediator of the JNK pathway
- Two alternatively spliced transcripts encoding distinct isoforms have been described
- [provided by RefSeq Sequence: AASRPSPSGGDSVLPKSISSAHDTRGSSVPENDRLASIAAELQFRSLSRHSSPTEERDEPAYPRGDSSGSTRRSWELRTLISQSKDTASKLGPIEAIQKS
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Antigen: mitogen-activated protein kinase kinase kinase 4
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_005922
Gene Symbols: MAP3K4
Immunogen: MAP3K4 (NP_005913, 1201 a.a. ∼ 1300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity: 100 μg
Research Discipline: Kinases
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
Clone: 4F10
Description: Mouse monoclonal antibody raised against a partial recombinant MAP3K4.
Gene: MAP3K4
Gene Alias: FLJ42439/KIAA0213/MAPKKK4/MEKK4/MTK1/PRO0412
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Whole Molecule: Yes
Gene ID (Entrez): 4216
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1 κ
Antigen:
mitogen-activated protein kinase kinase kinase 4
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_005922
Gene Symbols:
MAP3K4
Immunogen:
MAP3K4 (NP_005913, 1201 a.a. ∼ 1300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity:
100 μg
Research Discipline:
Kinases
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Clone:
4F10
Description:
Mouse monoclonal antibody raised against a partial recombinant MAP3K4.
Gene:
MAP3K4
Gene Alias:
FLJ42439/KIAA0213/MAPKKK4/MEKK4/MTK1/PRO0412
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Whole Molecule:
Yes
Gene ID (Entrez):
4216
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1 κ
Antigen: mesenchyme homeobox 1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_004527
Gene Symbols: MEOX1
Immunogen: MEOX1 (NP_004518, 82 a.a. ∼ 170 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity: 100 μg
Research Discipline: Transcription Regulation
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Applications: ELISA, Western Blot
Clone: 3D6
Description: Mouse monoclonal antibody raised against a full length recombinant MEOX1.
Gene: MEOX1
Gene Alias: MOX1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Whole Molecule: Yes
Gene ID (Entrez): 4222
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a κ
Antigen:
mesenchyme homeobox 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_004527
Gene Symbols:
MEOX1
Immunogen:
MEOX1 (NP_004518, 82 a.a. ∼ 170 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity:
100 μg
Research Discipline:
Transcription Regulation
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Applications:
ELISA, Western Blot
Clone:
3D6
Description:
Mouse monoclonal antibody raised against a full length recombinant MEOX1.
Gene:
MEOX1
Gene Alias:
MOX1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Whole Molecule:
Yes
Gene ID (Entrez):
4222
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a κ
Antigen: mesenchyme homeobox 2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: BC017021
Gene Symbols: MEOX2
Immunogen: MEOX2 (AAH17021, 1 a.a. ∼ 303 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity: 100 μg
Research Discipline: __
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Applications: ELISA, Immunofluorescence, Western Blot
Clone: 5A6
Description: Mouse monoclonal antibody raised against a full length recombinant MEOX2.
Gene: MEOX2
Gene Alias: GAX/MOX2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Whole Molecule: Yes
Gene ID (Entrez): 4223
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1 κ
Antigen:
mesenchyme homeobox 2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
BC017021
Gene Symbols:
MEOX2
Immunogen:
MEOX2 (AAH17021, 1 a.a. ∼ 303 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity:
100 μg
Research Discipline:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Applications:
ELISA, Immunofluorescence, Western Blot
Clone:
5A6
Description:
Mouse monoclonal antibody raised against a full length recombinant MEOX2.
Gene:
MEOX2
Gene Alias:
GAX/MOX2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Whole Molecule:
Yes
Gene ID (Entrez):
4223
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1 κ
Antigen: KIT ligand
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_003994
Gene Symbols: KITLG
Immunogen: KITLG (NP_003985, 26 a.a. ∼ 245 a.a) partial recombinant protein.
Quantity: 100 μg
Research Discipline: Cell Adhesion
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Applications: ELISA
Clone: 3C7
Description: Mouse monoclonal antibody raised against a partial recombinant KITLG.
Gene: KITLG
Gene Alias: DKFZp686F2250/KL-1/Kitl/MGF/SCF/SF/SHEP7
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Whole Molecule: Yes
Gene ID (Entrez): 4254
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG2a κ
Antigen:
KIT ligand
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_003994
Gene Symbols:
KITLG
Immunogen:
KITLG (NP_003985, 26 a.a. ∼ 245 a.a) partial recombinant protein.
Quantity:
100 μg
Research Discipline:
Cell Adhesion
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Applications:
ELISA
Clone:
3C7
Description:
Mouse monoclonal antibody raised against a partial recombinant KITLG.
Gene:
KITLG
Gene Alias:
DKFZp686F2250/KL-1/Kitl/MGF/SCF/SF/SHEP7
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Whole Molecule:
Yes
Gene ID (Entrez):
4254
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG2a κ