89-001-122

noggin, Mouse, Clone: 4C9, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-001-122-Each-of-1 In Stock ₹ 41,239.92

89-001-122 - Each of 1

₹ 41,239.92

In Stock

Quantity

1

Base Price: ₹ 41,239.92

GST (18%): ₹ 7,423.186

Total Price: ₹ 48,663.106

Antigen

noggin

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC034027

Gene Symbols

NOG

Immunogen

NOG (AAH34027, 28 a.a. ∼ 232 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Neurobiology

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Western Blot

Clone

4C9

Description

Mouse monoclonal antibody raised against a full length recombinant NOG.

Gene

NOG

Gene Alias

SYM1/SYNS1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

9241

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2b κ

Description

  • The secreted polypeptide, encoded by this gene, binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP4)
  • By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, this protein may have a principal role in creating morphogenic gradients
  • The protein appears to have pleiotropic effect, both early in development as well as in later stages
  • It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment
  • The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes, such as neural tube fusion and joint formation
  • Recently, several dominant human NOG mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) were identified; both SYM1 and SYNS1 have multiple joint fusion as their principal feature, and map to the same region (17q22) as this gene
  • All of these mutations altered evolutionarily conserved amino acid residues
  • The amino acid sequence of this human gene is highly homologous to that of Xenopus, rat and mouse
  • [provided by RefSeq Sequence: QHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGAAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC

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Abnova Corporation

89-001-122

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Antigen:
noggin

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC034027

Gene Symbols:
NOG

Immunogen:
NOG (AAH34027, 28 a.a. ∼ 232 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Research Discipline:
Neurobiology

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Clone:
4C9

Description:
Mouse monoclonal antibody raised against a full length recombinant NOG.

Gene:
NOG

Gene Alias:
SYM1/SYNS1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
9241

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2b κ

Img

Abnova Corporation

89-001-123

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Antigen:
mitogen-activated protein kinase-activated protein kinase 2

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_032960

Gene Symbols:
MAPKAPK2

Immunogen:
MAPKAPK2 (NP_116584, 266 a.a. ∼ 352 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Research Discipline:
Kinases

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Clone:
3B8

Description:
Mouse monoclonal antibody raised against a full length recombinant MAPKAPK2.

Gene:
MAPKAPK2

Gene Alias:
MK2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
9261

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a κ

Img

Abnova Corporation

89-001-124

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Antigen:
serine/threonine kinase 17a

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC047696

Gene Symbols:
STK17A

Immunogen:
STK17A (AAH47696, 301 a.a. ∼ 413 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Research Discipline:
Apoptosis

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Applications:
ELISA, Western Blot

Clone:
3G8

Description:
Mouse monoclonal antibody raised against a partial recombinant STK17A.

Gene:
STK17A

Gene Alias:
DRAK1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
9263

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a κ

Img

Abnova Corporation

89-001-125

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Antigen:
CD83

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC030830

Gene Symbols:
CD83

Immunogen:
CD83 (AAH30830, 1 a.a. ∼ 205 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Research Discipline:
__

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Clone:
3F3

Description:
Mouse monoclonal antibody raised against a full length recombinant CD83.

Gene:
CD83

Gene Alias:
BL11/HB15

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
9308

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG2a κ