89-004-050

core-binding factor, beta subunit, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-004-050-Each-of-1 In Stock ₹ 29,603.76

89-004-050 - Each of 1

₹ 29,603.76

In Stock

Quantity

1

Base Price: ₹ 29,603.76

GST (18%): ₹ 5,328.677

Total Price: ₹ 34,932.437

Antigen

core-binding factor, beta subunit

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant CBFB.

Gene

CBFB

Gene Alias

PEBP2B

Host Species

Mouse

Quantity

50 μL

Research Discipline

Transcription Regulation

Primary or Secondary

Primary

Target Species

Human

Form

Serum

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_001755

Gene Symbols

CBFB

Immunogen

CBFB (NP_001746, 74 a.a. ∼ 163 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

865

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2)
  • The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters
  • Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus
  • In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11
  • This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype
  • Two transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq Sequence: QGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREE

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-004-050

--


Antigen:
core-binding factor, beta subunit

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant CBFB.

Gene:
CBFB

Gene Alias:
PEBP2B

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Transcription Regulation

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001755

Gene Symbols:
CBFB

Immunogen:
CBFB (NP_001746, 74 a.a. ∼ 163 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
865

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-004-053

--


Antigen:
cyclin G1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant CCNG1.

Gene:
CCNG1

Gene Alias:
CCNG

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Cell Cycle

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
BC000196

Gene Symbols:
CCNG1

Immunogen:
CCNG1 (AAH00196, 1 a.a. ∼ 110 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
900

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-004-054

--


Antigen:
CD8a

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant CD8A.

Gene:
CD8A

Gene Alias:
CD8/Leu2/MAL/p32

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Signal Transduction

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001768

Gene Symbols:
CD8A

Immunogen:
CD8A (NP_001759, 22 a.a. ∼ 131 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
925

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-004-055

--


Antigen:
CD68 molecule

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant CD68.

Gene:
CD68

Gene Alias:
DKFZp686M18236/GP110/SCARD1

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001251

Gene Symbols:
CD68

Immunogen:
CD68 (NP_001242, 164 a.a. ∼ 262 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
968

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.