89-004-409

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-004-409-Each-of-1 In Stock ₹ 29,603.76

89-004-409 - Each of 1

₹ 29,603.76

In Stock

Quantity

1

Base Price: ₹ 29,603.76

GST (18%): ₹ 5,328.677

Total Price: ₹ 34,932.437

Antigen

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant DDEF2.

Gene

ASAP2

Gene Alias

AMAP2/CENTB3/DDEF2/FLJ42910/KIAA0400/PAG3/PAP/Pap-alpha/SHAG1

Host Species

Mouse

Quantity

50 μL

Whole Molecule

Yes

Gene ID (Entrez)

8853

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_003887

Gene Symbols

ASAP2

Immunogen

DDEF2 (NP_003878, 909 a.a. ∼ 1006 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Serum

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Description

  • This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain
  • The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2)
  • The encoded protein forms a stable complex with PYK2 in vivo
  • This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2
  • The encoded protein is tyrosine phosphorylated by activated PYK2
  • It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity
  • The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes
  • In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport
  • Multiple transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq Sequence: RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD

Compare Similar Items

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Abnova Corporation

89-004-409

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Antigen:
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant DDEF2.

Gene:
ASAP2

Gene Alias:
AMAP2/CENTB3/DDEF2/FLJ42910/KIAA0400/PAG3/PAP/Pap-alpha/SHAG1

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
8853

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_003887

Gene Symbols:
ASAP2

Immunogen:
DDEF2 (NP_003878, 909 a.a. ∼ 1006 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

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Abnova Corporation

89-004-410

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Antigen:
Rho guanine nucleotide exchange factor (GEF) 7

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant ARHGEF7.

Gene:
ARHGEF7

Gene Alias:
BETA-PIX/COOL1/DKFZp686C12170/DKFZp761K1021/KIAA0142/KIAA0412/Nbla10314/P50/P50BP/P85/P85COOL1/P85SPR/PAK3/PIXB

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
8874

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_145735

Gene Symbols:
ARHGEF7

Immunogen:
ARHGEF7 (NP_663788, 102 a.a. ∼ 190 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Img

Abnova Corporation

89-004-412

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Antigen:
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant EIF2B5.

Gene:
EIF2B5

Gene Alias:
CACH/CLE/EIF-2B/EIF2Bepsilon/LVWM

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
8893

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_003907

Gene Symbols:
EIF2B5

Immunogen:
EIF2B5 (NP_003898, 622 a.a. ∼ 720 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

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89-004-413

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Antigen:
adaptor-related protein complex 1, mu 1 subunit

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant AP1M1.

Gene:
AP1M1

Gene Alias:
AP47/CLAPM2/CLTNM/MU-1A

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
8907

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_032493

Gene Symbols:
AP1M1

Immunogen:
AP1M1 (NP_115882, 1 a.a. ∼ 74 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum