89-005-988

proopiomelanocortin (B01), Mouse anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-005-988-Each-of-1 In Stock ₹ 41,239.92

89-005-988 - Each of 1

₹ 41,239.92

In Stock

Quantity

1

Base Price: ₹ 41,239.92

GST (18%): ₹ 7,423.186

Total Price: ₹ 48,663.106

Antigen

proopiomelanocortin

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human POMC protein.

Gene

POMC

Gene Alias

ACTH/CLIP/LPH/MSH/NPP/POC

Host Species

Mouse

Quantity

50 μL

Research Discipline

Neurobiology

Primary or Secondary

Primary

Target Species

Human

Form

Serum

Applications

Western Blot

Conjugate

Unconjugated

Formulation

No additive

Gene Accession No.

NM_000939

Gene Symbols

POMC

Immunogen

POMC (NP_000930, 1 a.a. ∼ 267 a.a) full-length human protein.

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

5443

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases
  • There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions
  • The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products
  • In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation
  • These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides
  • Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation
  • Alternatively spliced transcript variants encoding the same protein have been described
  • [provided by RefSeq Sequence: MPRSCCSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLLECIRACKPDLSAETPMFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNSSSSGSSGAGQKREDVSAGEDCGPLPEGGPEPRSDGAKPGPREGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELTGQRLREGDGPDGPADDGAGAQADLEHSLLVAAEKKDEGPYRMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-005-988

--


Antigen:
proopiomelanocortin

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human POMC protein.

Gene:
POMC

Gene Alias:
ACTH/CLIP/LPH/MSH/NPP/POC

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Neurobiology

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
NM_000939

Gene Symbols:
POMC

Immunogen:
POMC (NP_000930, 1 a.a. ∼ 267 a.a) full-length human protein.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
5443

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-005-991

--


Antigen:
POU class 2 homeobox 2

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human POU2F2 protein.

Gene:
POU2F2

Gene Alias:
OCT2/OTF2/Oct-2

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Transcription Regulation

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
BC006101.1

Gene Symbols:
POU2F2

Immunogen:
POU2F2 (AAH06101.1, 1 a.a. ∼ 400 a.a) full-length human protein.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
5452

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-006-012

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Antigen:
protein phosphatase 2, regulatory subunit B', alpha isoform

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human PPP2R5A protein.

Gene:
PPP2R5A

Gene Alias:
B56A/MGC131915/PR61A

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
NM_006243.2

Gene Symbols:
PPP2R5A

Immunogen:
PPP2R5A (NP_006234.1, 1 a.a. ∼ 486 a.a) full-length human protein.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
5525

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-006-044

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Antigen:
protein C (inactivator of coagulation factors Va and VIIIa)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human PROC protein.

Gene:
PROC

Gene Alias:
PC/PROC1

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Apoptosis

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
NM_000312

Gene Symbols:
PROC

Immunogen:
PROC (NP_000303, 1 a.a. ∼ 461 a.a) full-length human protein.

Regulatory Status:
RUO

Whole Molecule:
Yes

Gene ID (Entrez):
5624

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.