89-007-078

cleavage and polyadenylation specific factor 4, 30kDa, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-007-078-Each-of-1 In Stock ₹ 41,239.92

89-007-078 - Each of 1

₹ 41,239.92

In Stock

Quantity

1

Base Price: ₹ 41,239.92

GST (18%): ₹ 7,423.186

Total Price: ₹ 48,663.106

Antigen

cleavage and polyadenylation specific factor 4, 30kDa

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human CPSF4 protein.

Gene

CPSF4

Gene Alias

CPSF30/NAR/NEB1

Host Species

Mouse

Quantity

50 μL

Whole Molecule

Yes

Gene ID (Entrez)

10898

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications

Western Blot

Conjugate

Unconjugated

Formulation

No additive

Gene Accession No.

BC003101

Gene Symbols

CPSF4

Immunogen

CPSF4 (AAH03101, 1 a.a. ∼ 244 a.a) full-length human protein.

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Serum

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Description

  • Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain
  • The NS1 effector domain functionally interacts with the cellular 30kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs
  • In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit
  • Binding of the NS1 protein to the 30kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs
  • Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs
  • Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene
  • [provided by RefSeq] Sequence: MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-007-078

--


Antigen:
cleavage and polyadenylation specific factor 4, 30kDa

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human CPSF4 protein.

Gene:
CPSF4

Gene Alias:
CPSF30/NAR/NEB1

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
10898

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
BC003101

Gene Symbols:
CPSF4

Immunogen:
CPSF4 (AAH03101, 1 a.a. ∼ 244 a.a) full-length human protein.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

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Abnova Corporation

89-007-086

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Antigen:
COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human COPS8 protein.

Gene:
COPS8

Gene Alias:
COP9/CSN8/MGC1297/MGC43256/SGN8

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
10920

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
BC003090

Gene Symbols:
COPS8

Immunogen:
COPS8 (AAH03090, 1 a.a. ∼ 209 a.a) full-length human protein.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Serum

Img

Abnova Corporation

89-007-092

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Antigen:
male-specific lethal 3 homolog (Drosophila)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human MSL3L1 protein.

Gene:
MSL3

Gene Alias:
DKFZp586J1822/MSL3L1

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
10943

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
BC031210.1

Gene Symbols:
MSL3

Immunogen:
MSL3L1 (AAH31210.1, 1 a.a. ∼ 521 a.a) full-length human protein.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Serum

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Antigen:
tripartite motif-containing 31

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human TRIM31 protein.

Gene:
TRIM31

Gene Alias:
C6orf13/HCG1/HCGI/RNF

Host Species:
Mouse

Quantity:
50 μL

Whole Molecule:
Yes

Gene ID (Entrez):
11074

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
No additive

Gene Accession No.:
BC017017

Gene Symbols:
TRIM31

Immunogen:
TRIM31 (AAH17017, 1 a.a. ∼ 425 a.a) full-length human protein.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum