89-016-928

uromodulin, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-016-928-Each-of-1 In Stock ₹ 44,662.32

89-016-928 - Each of 1

₹ 44,662.32

In Stock

Quantity

1

Base Price: ₹ 44,662.32

GST (18%): ₹ 8,039.218

Total Price: ₹ 52,701.538

Antigen

uromodulin

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human UMOD protein.

Gene

UMOD

Gene Alias

ADMCKD2/FJHN/HNFJ/MCKD2/THGP/THP

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC035975

Gene Symbols

UMOD

Immunogen

UMOD (AAH35975, 1 a.a. ∼ 611 a.a) full-length human protein.

Quantity

50 μg

Research Discipline

Cell Cycle

Gene ID (Entrez)

7369

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • This gene encodes uromodulin, the most abundant protein in normal urine
  • Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle
  • Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids
  • Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria
  • Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN)
  • These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure
  • While several transcript variants may exist for this gene, the full-length natures of only two have been described to date
  • These two represent the major variants of this gene and encode the same isoform
  • [provided by RefSeq Sequence: MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRPHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ

Compare Similar Items

Show Difference

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Antigen:
uromodulin

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human UMOD protein.

Gene:
UMOD

Gene Alias:
ADMCKD2/FJHN/HNFJ/MCKD2/THGP/THP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC035975

Gene Symbols:
UMOD

Immunogen:
UMOD (AAH35975, 1 a.a. ∼ 611 a.a) full-length human protein.

Quantity:
50 μg

Research Discipline:
Cell Cycle

Gene ID (Entrez):
7369

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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Antigen:
uroporphyrinogen III synthase

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human UROS protein.

Gene:
UROS

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_000375.1

Gene Symbols:
UROS

Immunogen:
UROS (NP_000366.1, 1 a.a. ∼ 265 a.a) full-length human protein.

Quantity:
50 μg

Research Discipline:
__

Gene ID (Entrez):
7390

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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Antigen:
ubiquitin specific peptidase 1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human USP1 protein.

Gene:
USP1

Gene Alias:
UBP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_003368.4

Gene Symbols:
USP1

Immunogen:
USP1 (NP_003359.3, 1 a.a. ∼ 785 a.a) full-length human protein.

Quantity:
50 μg

Research Discipline:
Ubiquitin/Proteasome

Gene ID (Entrez):
7398

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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Antigen:
X-box binding protein 1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a full-length human XBP1 protein.

Gene:
XBP1

Gene Alias:
TREB5/XBP2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_005080.2

Gene Symbols:
XBP1

Immunogen:
XBP1 (NP_005071.2, 1 a.a. ∼ 261 a.a) full-length human protein.

Quantity:
50 μg

Research Discipline:
Transcription Regulation

Gene ID (Entrez):
7494

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG