89-017-410
anti-CHEK2 Matched Antibody Pair, Abnova
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-017-410-Each-of-1 | In Stock | ₹ 95,827.20 |
89-017-410 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 95,827.20
GST (18%): ₹ 17,248.896
Total Price: ₹ 1,13,076.096
Antigen
CHEK2
Classification
Monoclonal/Polyclonal
Description
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CHEK2.
Gene Alias
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species
Mouse, Rabbit
Quantity
1 Set
Research Discipline
Cell Cycle
Gene ID (Entrez)
11200
Target Species
Human
Isotype
IgG2a
Applications
ELISA
Conjugate
Unconjugated
Gene
CHEK2
Gene Symbols
CHEK2
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Includes
Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-CHEK2 (100 μg) 2. Detection antibody: mouse monoclonal anti-CHEK2, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Description
- In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators
- The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
- It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage
- When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage
- Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors
- This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases
- Three transcript variants encoding different isoforms have been found for this gene
- ELISA
Compare Similar Items
Show Difference
Antigen: CHEK2
Classification: Monoclonal/Polyclonal
Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CHEK2.
Gene Alias: CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species: Mouse, Rabbit
Quantity: 1 Set
Research Discipline: Cell Cycle
Gene ID (Entrez): 11200
Target Species: Human
Isotype: IgG2a
Applications: ELISA
Conjugate: Unconjugated
Gene: CHEK2
Gene Symbols: CHEK2
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-CHEK2 (100 μg) 2. Detection antibody: mouse monoclonal anti-CHEK2, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen:
CHEK2
Classification:
Monoclonal/Polyclonal
Description:
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CHEK2.
Gene Alias:
CDS1/CHK2/HuCds1/LFS2/PP1425/RAD53
Host Species:
Mouse, Rabbit
Quantity:
1 Set
Research Discipline:
Cell Cycle
Gene ID (Entrez):
11200
Target Species:
Human
Isotype:
IgG2a
Applications:
ELISA
Conjugate:
Unconjugated
Gene:
CHEK2
Gene Symbols:
CHEK2
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Includes:
Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-CHEK2 (100 μg) 2. Detection antibody: mouse monoclonal anti-CHEK2, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen: CCRK
Classification: Monoclonal/Polyclonal
Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CCRK.
Gene Alias: CDCH/p42
Host Species: Mouse, Rabbit
Quantity: 1 Set
Research Discipline: __
Gene ID (Entrez): 23552
Target Species: Human
Isotype: IgG2a
Applications: ELISA
Conjugate: Unconjugated
Gene: CCRK
Gene Symbols: CCRK
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-CCRK (100 μg) 2. Detection antibody: mouse monoclonal anti-CCRK, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen:
CCRK
Classification:
Monoclonal/Polyclonal
Description:
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CCRK.
Gene Alias:
CDCH/p42
Host Species:
Mouse, Rabbit
Quantity:
1 Set
Research Discipline:
__
Gene ID (Entrez):
23552
Target Species:
Human
Isotype:
IgG2a
Applications:
ELISA
Conjugate:
Unconjugated
Gene:
CCRK
Gene Symbols:
CCRK
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Includes:
Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-CCRK (100 μg) 2. Detection antibody: mouse monoclonal anti-CCRK, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen: ZNF346
Classification: Monoclonal/Polyclonal
Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human ZNF346.
Gene Alias: DKFZp547M223/JAZ/Zfp346
Host Species: Mouse, Rabbit
Quantity: 1 Set
Research Discipline: __
Gene ID (Entrez): 23567
Target Species: Human
Isotype: __
Applications: ELISA
Conjugate: Unconjugated
Gene: ZNF346
Gene Symbols: ZNF346
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-ZNF346 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-ZNF346 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen:
ZNF346
Classification:
Monoclonal/Polyclonal
Description:
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human ZNF346.
Gene Alias:
DKFZp547M223/JAZ/Zfp346
Host Species:
Mouse, Rabbit
Quantity:
1 Set
Research Discipline:
__
Gene ID (Entrez):
23567
Target Species:
Human
Isotype:
__
Applications:
ELISA
Conjugate:
Unconjugated
Gene:
ZNF346
Gene Symbols:
ZNF346
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Includes:
Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-ZNF346 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-ZNF346 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen: COBRA1
Classification: Monoclonal/Polyclonal
Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human COBRA1.
Gene Alias: DKFZp586B0519/KIAA1182/NELF-B/NELFB
Host Species: Mouse, Rabbit
Quantity: 1 Set
Research Discipline: __
Gene ID (Entrez): 25920
Target Species: Human
Isotype: __
Applications: ELISA
Conjugate: Unconjugated
Gene: COBRA1
Gene Symbols: COBRA1
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-COBRA1 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-COBRA1 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Antigen:
COBRA1
Classification:
Monoclonal/Polyclonal
Description:
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human COBRA1.
Gene Alias:
DKFZp586B0519/KIAA1182/NELF-B/NELFB
Host Species:
Mouse, Rabbit
Quantity:
1 Set
Research Discipline:
__
Gene ID (Entrez):
25920
Target Species:
Human
Isotype:
__
Applications:
ELISA
Conjugate:
Unconjugated
Gene:
COBRA1
Gene Symbols:
COBRA1
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Includes:
Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-COBRA1 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-COBRA1 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Content And Storage:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.