89-017-468

anti-CALR, MaxPab™ Polyclonal, Abnova

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-017-468-Each-of-1 In Stock ₹ 47,742.48

89-017-468 - Each of 1

₹ 47,742.48

In Stock

Quantity

1

Base Price: ₹ 47,742.48

GST (18%): ₹ 8,593.646

Total Price: ₹ 56,336.126

Antigen

calreticulin

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a full-length human CALR protein.

Gene

CALR

Gene Alias

CRT/FLJ26680/RO/SSA/cC1qR

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

811

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

Applications

In situ PLA, Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_004343.2

Gene Symbols

CALR

Immunogen

CALR (NP_004334.1, 1 a.a. ∼ 417 a.a) full-length human protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum
  • It is also found in the nucleus, suggesting that it may have a role in transcription regulation
  • Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors
  • Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium
  • The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element
  • Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation
  • Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors
  • Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen
  • Earlier papers referred to calreticulin as an Ro/SS-A antigen but this was later disproven
  • Increased autoantibody titer against human calreticulin is found in infants with complete congenital heart block of both the IgG and IgM classes
  • [provided by RefSeq Host Species: Rabbit Species Reactivity [for Features Main]: Human Immunogen: CALR (NP_004334.1, 1 a.a
  • ∽ 417 a.a) full-length human protein
  • Detection Antibody, In situ PLA, Western Blotting

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-017-468

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Antigen:
calreticulin

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human CALR protein.

Gene:
CALR

Gene Alias:
CRT/FLJ26680/RO/SSA/cC1qR

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
811

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_004343.2

Gene Symbols:
CALR

Immunogen:
CALR (NP_004334.1, 1 a.a. ∼ 417 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Abnova Corporation

89-017-469

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Antigen:
calcium/calmodulin-dependent protein kinase IV

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human CAMK4 protein.

Gene:
CAMK4

Gene Alias:
CaMK-GR/MGC36771

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
814

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001744.3

Gene Symbols:
CAMK4

Immunogen:
CAMK4 (NP_001735.1, 1 a.a. ∼ 473 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Abnova Corporation

89-017-470

--


Antigen:
calcium/calmodulin-dependent protein kinase II gamma

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human CAMK2G protein.

Gene:
CAMK2G

Gene Alias:
CAMK/CAMK-II/CAMKG/FLJ16043/MGC26678

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
818

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC034044.1

Gene Symbols:
CAMK2G

Immunogen:
CAMK2G (AAH34044.1, 1 a.a. ∼ 527 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Abnova Corporation

89-017-471

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Antigen:
calcium modulating ligand

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human CAMLG protein.

Gene:
CAMLG

Gene Alias:
CAML/MGC163197

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
819

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001745.2

Gene Symbols:
CAMLG

Immunogen:
CAMLG (NP_001736.1, 1 a.a. ∼ 296 a.a) full-length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody