89-017-682

GNAS complex locus, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-017-682-Each-of-1 In Stock ₹ 47,742.48

89-017-682 - Each of 1

₹ 47,742.48

In Stock

Quantity

1

Base Price: ₹ 47,742.48

GST (18%): ₹ 8,593.646

Total Price: ₹ 56,336.126

Antigen

GNAS complex locus

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a full-length human GNAS protein.

Gene

GNAS

Gene Alias

AHO/C20orf45/GNAS1/GPSA/GSA/GSP/MGC33735/NESP/PHP1A/PHP1B/POH/dJ309F20.1.1/dJ806M20.3.3

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

In situ PLA, Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000516

Gene Symbols

GNAS

Immunogen

GNAS (NP_000507.1, 1 a.a. ∼ 394 a.a) full-length human protein.

Quantity

100 μg

Research Discipline

Signal Transduction

Gene ID (Entrez)

2778

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • This locus has a highly complex imprinted expression pattern
  • It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons
  • Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression
  • An antisense transcript is produced from an overlapping locus on the opposite strand
  • One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region
  • In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex
  • Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses
  • Multiple transcript variants encoding different isoforms have been found for this gene
  • Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
  • [provided by RefSeq] Sequence: MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL

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Abnova Corporation

89-017-682

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Antigen:
GNAS complex locus

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human GNAS protein.

Gene:
GNAS

Gene Alias:
AHO/C20orf45/GNAS1/GPSA/GSA/GSP/MGC33735/NESP/PHP1A/PHP1B/POH/dJ309F20.1.1/dJ806M20.3.3

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_000516

Gene Symbols:
GNAS

Immunogen:
GNAS (NP_000507.1, 1 a.a. ∼ 394 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Signal Transduction

Gene ID (Entrez):
2778

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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Antigen:
guanine nucleotide binding protein (G protein), gamma 7

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human GNG7 protein.

Gene:
GNG7

Gene Alias:
FLJ00058

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_052847

Gene Symbols:
GNG7

Immunogen:
GNG7 (NP_443079.1, 1 a.a. ∼ 68 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
2788

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Img

Abnova Corporation

89-017-684

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Antigen:
golgi autoantigen, golgin subfamily a, 1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human GOLGA1 protein.

Gene:
GOLGA1

Gene Alias:
MGC33154/golgin-97

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
BC032853.1

Gene Symbols:
GOLGA1

Immunogen:
GOLGA1 (AAH32853.1, 1 a.a. ∼ 767 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
2800

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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89-017-685

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Antigen:
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human GOT1 protein.

Gene:
GOT1

Gene Alias:
GIG18

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_002079

Gene Symbols:
GOT1

Immunogen:
GOT1 (NP_002070.1, 1 a.a. ∼ 413 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
2805

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG