89-018-012

Fas (TNF receptor superfamily, member 6), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-018-012-Each-of-1 In Stock ₹ 47,742.48

89-018-012 - Each of 1

₹ 47,742.48

In Stock

Quantity

1

Base Price: ₹ 47,742.48

GST (18%): ₹ 8,593.646

Total Price: ₹ 56,336.126

Antigen

Fas (TNF receptor superfamily, member 6)

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a full-length human FAS protein.

Gene

FAS

Gene Alias

ALPS1A/APO-1/APT1/CD95/FAS1/FASTM/TNFRSF6

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

In situ PLA, Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000043

Gene Symbols

FAS

Immunogen

FAS (NP_000034.1, 1 a.a. ∼ 335 a.a) full-length human protein.

Quantity

100 μg

Research Discipline

Apoptosis

Gene ID (Entrez)

355

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • The protein encoded by this gene is a member of the TNF-receptor superfamily
  • This receptor contains a death domain
  • It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system
  • The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10
  • The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis
  • This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells
  • At least eight alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated decay (NMD)
  • The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform
  • [provided by RefSeq Sequence: MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLTSNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLV

Compare Similar Items

Show Difference

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Abnova Corporation

89-018-012

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Antigen:
Fas (TNF receptor superfamily, member 6)

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human FAS protein.

Gene:
FAS

Gene Alias:
ALPS1A/APO-1/APT1/CD95/FAS1/FASTM/TNFRSF6

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_000043

Gene Symbols:
FAS

Immunogen:
FAS (NP_000034.1, 1 a.a. ∼ 335 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Apoptosis

Gene ID (Entrez):
355

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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Abnova Corporation

89-018-013

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Antigen:
Fas ligand (TNF superfamily, member 6)

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human FASLG protein.

Gene:
FASLG

Gene Alias:
APT1LG1/CD178/CD95L/FASL/TNFSF6

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_000639

Gene Symbols:
FASLG

Immunogen:
FASLG (AAH17502.1, 1 a.a. ∼ 281 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Apoptosis

Gene ID (Entrez):
356

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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89-018-014

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Antigen:
v-raf murine sarcoma 3611 viral oncogene homolog

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human ARAF protein.

Gene:
ARAF

Gene Alias:
A-RAF/ARAF1/PKS2/RAFA1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Immunofluorescence, In situ PLA, Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001654.1

Gene Symbols:
ARAF

Immunogen:
ARAF (NP_001645.1, 1 a.a. ∼ 606 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Kinases

Gene ID (Entrez):
369

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

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89-018-015

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Antigen:
tripartite motif-containing 23

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human TRIM23 protein.

Gene:
TRIM23

Gene Alias:
ARD1/ARFD1/RNF46

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001656

Gene Symbols:
TRIM23

Immunogen:
TRIM23 (NP_001647.1, 1 a.a. ∼ 574 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Signal Transduction

Gene ID (Entrez):
373

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG