89-018-378
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-018-378-Each-of-1 | In Stock | ₹ 47,742.48 |
89-018-378 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,742.48
GST (18%): ₹ 8,593.646
Total Price: ₹ 56,336.126
Antigen
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against a full-length human PRKAR1A protein.
Gene
PRKAR1A
Gene Alias
CAR/CNC/CNC1/DKFZp779L0468/MGC17251/PKR1/PPNAD1/PRKAR1/TSE1
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
5573
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_002734
Gene Symbols
PRKAR1A
Immunogen
PRKAR1A (NP_002725.1, 1 a.a. ∼ 381 a.a) full-length human protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Description
- cAMP is a signaling molecule important for a variety of cellular functions
- cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins
- The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits
- cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
- Four different regulatory subunits and three catalytic subunits have been identified in humans
- This gene encodes one of the regulatory subunits
- This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids
- Mutations in this gene cause Carney complex (CNC)
- This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2
- A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)
- Three alternatively spliced transcript variants encoding the same protein have been observed
- [provided by RefSeq Sequence: MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
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Antigen: protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against a full-length human PRKAR1A protein.
Gene: PRKAR1A
Gene Alias: CAR/CNC/CNC1/DKFZp779L0468/MGC17251/PKR1/PPNAD1/PRKAR1/TSE1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 5573
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_002734
Gene Symbols: PRKAR1A
Immunogen: PRKAR1A (NP_002725.1, 1 a.a. ∼ 381 a.a) full-length human protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a full-length human PRKAR1A protein.
Gene:
PRKAR1A
Gene Alias:
CAR/CNC/CNC1/DKFZp779L0468/MGC17251/PKR1/PPNAD1/PRKAR1/TSE1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
5573
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_002734
Gene Symbols:
PRKAR1A
Immunogen:
PRKAR1A (NP_002725.1, 1 a.a. ∼ 381 a.a) full-length human protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: protein kinase C, delta
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against a full-length human PRKCD protein.
Gene: PRKCD
Gene Alias: MAY1/MGC49908/PKCD/nPKC-delta
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 5580
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Applications: In situ PLA, Western Blot
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_006254.3
Gene Symbols: PRKCD
Immunogen: PRKCD (NP_006245.2, 1 a.a. ∼ 676 a.a) full-length human protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
protein kinase C, delta
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a full-length human PRKCD protein.
Gene:
PRKCD
Gene Alias:
MAY1/MGC49908/PKCD/nPKC-delta
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
5580
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Applications:
In situ PLA, Western Blot
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_006254.3
Gene Symbols:
PRKCD
Immunogen:
PRKCD (NP_006245.2, 1 a.a. ∼ 676 a.a) full-length human protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: mitogen-activated protein kinase 3
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against a full-length human MAPK3 protein.
Gene: MAPK3
Gene Alias: ERK1/HS44KDAP/HUMKER1A/MGC20180/P44ERK1/P44MAPK/PRKM3
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 5595
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Applications: In situ PLA, Western Blot
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_002746.2
Gene Symbols: MAPK3
Immunogen: MAPK3 (AAH13992.1, 1 a.a. ∼ 379 a.a) full-length human protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
mitogen-activated protein kinase 3
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a full-length human MAPK3 protein.
Gene:
MAPK3
Gene Alias:
ERK1/HS44KDAP/HUMKER1A/MGC20180/P44ERK1/P44MAPK/PRKM3
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
5595
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Applications:
In situ PLA, Western Blot
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_002746.2
Gene Symbols:
MAPK3
Immunogen:
MAPK3 (AAH13992.1, 1 a.a. ∼ 379 a.a) full-length human protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: mitogen-activated protein kinase 8
Classification: Polyclonal
Description: Rabbit polyclonal antibody raised against a full-length human MAPK8 protein.
Gene: MAPK8
Gene Alias: JNK/JNK1/JNK1A2/JNK21B1/2/PRKM8/SAPK1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Gene ID (Entrez): 5599
Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG
Applications: Immunofluorescence, In situ PLA, Western Blot
Conjugate: Unconjugated
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: NM_139049
Gene Symbols: MAPK8
Immunogen: MAPK8 (NP_620637.1, 1 a.a. ∼ 427 a.a) full-length human protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Antigen:
mitogen-activated protein kinase 8
Classification:
Polyclonal
Description:
Rabbit polyclonal antibody raised against a full-length human MAPK8 protein.
Gene:
MAPK8
Gene Alias:
JNK/JNK1/JNK1A2/JNK21B1/2/PRKM8/SAPK1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Gene ID (Entrez):
5599
Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG
Applications:
Immunofluorescence, In situ PLA, Western Blot
Conjugate:
Unconjugated
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
NM_139049
Gene Symbols:
MAPK8
Immunogen:
MAPK8 (NP_620637.1, 1 a.a. ∼ 427 a.a) full-length human protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody