89-018-805

NLR family, pyrin domain containing 3, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-018-805-Each-of-1 In Stock ₹ 47,742.48

89-018-805 - Each of 1

₹ 47,742.48

In Stock

Quantity

1

Base Price: ₹ 47,742.48

GST (18%): ₹ 8,593.646

Total Price: ₹ 56,336.126

Antigen

NLR family, pyrin domain containing 3

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against a full-length human NLRP3 protein.

Gene

NLRP3

Gene Alias

AGTAVPRL/AII/AII/AVP/AVP/C1orf7/CIAS1/CLR1.1/FCAS/FCU/FLJ95925/MWS/NALP3/PYPAF1

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_004895

Gene Symbols

NLRP3

Immunogen

NLRP3 (NP_004886.3, 1 a.a. ∼ 1036 a.a) full-length human protein.

Quantity

100 μg

Research Discipline

Apoptosis

Gene ID (Entrez)

114548

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

Description

  • This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif
  • This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex
  • This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis
  • Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID)
  • Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene
  • Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid
  • [provided by RefSeq] Sequence: MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW

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Abnova Corporation

89-018-805

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Antigen:
NLR family, pyrin domain containing 3

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human NLRP3 protein.

Gene:
NLRP3

Gene Alias:
AGTAVPRL/AII/AII/AVP/AVP/C1orf7/CIAS1/CLR1.1/FCAS/FCU/FLJ95925/MWS/NALP3/PYPAF1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_004895

Gene Symbols:
NLRP3

Immunogen:
NLRP3 (NP_004886.3, 1 a.a. ∼ 1036 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
Apoptosis

Gene ID (Entrez):
114548

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Img

Abnova Corporation

89-018-806

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Antigen:
erythroblast membrane-associated protein (Scianna blood group)

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against a full-length human ERMAP protein.

Gene:
ERMAP

Gene Alias:
MGC118810/MGC118811/MGC118812/MGC118813/PRO2801/RD/SC

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
NM_001017922.1

Gene Symbols:
ERMAP

Immunogen:
ERMAP (NP_001017922.1, 1 a.a. ∼ 475 a.a) full-length human protein.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
114625

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG

Img

Abnova Corporation

89-018-808

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Antigen:
activin A receptor, type IIA

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant ACVR2A.

Gene:
ACVR2A

Gene Alias:
ACTRII/ACVR2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001616

Gene Symbols:
ACVR2A

Immunogen:
ACVR2A (AAH67418.1, 24 a.a. ∼ 133 a.a) partial recombinant protein with GST tag.

Quantity:
50 μL

Research Discipline:
Membrane Receptors

Gene ID (Entrez):
92

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
__

Img

Abnova Corporation

89-018-810

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Antigen:
B-cell CLL/lymphoma 2

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant BCL2.

Gene:
BCL2

Gene Alias:
Bcl-2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Applications:
ELISA

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
BC027258

Gene Symbols:
BCL2

Immunogen:
BCL2 (AAH27258, 140 a.a. ∼ 239 a.a) partial recombinant protein with GST tag.

Quantity:
50 μL

Research Discipline:
Apoptosis

Gene ID (Entrez):
596

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype:
__