89-018-824

class II, major histocompatibility complex, transactivator, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-018-824-Each-of-1 In Stock ₹ 31,773.00

89-018-824 - Each of 1

₹ 31,773.00

In Stock

Quantity

1

Base Price: ₹ 31,773.00

GST (18%): ₹ 5,719.14

Total Price: ₹ 37,492.14

Antigen

class II, major histocompatibility complex, transactivator

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant MHC2TA.

Gene

CIITA

Gene Alias

C2TA/CIITAIV/MHC2TA/NLRA

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Serum

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_000246

Gene Symbols

CIITA

Immunogen

MHC2TA (NP_000237, 39 a.a. ∼ 148 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

4261

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Description

  • This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain
  • The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the master control factor for the expression of these genes
  • The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus
  • Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion
  • Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction
  • [provided by RefSeq] Sequence: NSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFP

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Abnova Corporation

89-018-824

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Antigen:
class II, major histocompatibility complex, transactivator

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant MHC2TA.

Gene:
CIITA

Gene Alias:
C2TA/CIITAIV/MHC2TA/NLRA

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_000246

Gene Symbols:
CIITA

Immunogen:
MHC2TA (NP_000237, 39 a.a. ∼ 148 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4261

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-018-826

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Antigen:
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant MYBL1.

Gene:
MYBL1

Gene Alias:
A-MYB/AMYB/MGC120059/MGC120061

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
XM_034274

Gene Symbols:
MYBL1

Immunogen:
MYBL1 (XP_034274, 625 a.a. ∼ 734 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4603

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Antigen:
Notch homolog 2 (Drosophila)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant NOTCH2.

Gene:
NOTCH2

Gene Alias:
AGS2/hN2

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_024408

Gene Symbols:
NOTCH2

Immunogen:
NOTCH2 (NP_077719, 27 a.a. ∼ 136 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4853

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Antigen:
discoidin domain receptor tyrosine kinase 2

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant DDR2.

Gene:
DDR2

Gene Alias:
MIG20a/NTRKR3/TKT/TYRO10

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
BC052998

Gene Symbols:
DDR2

Immunogen:
DDR2 (AAH52998, 277 a.a. ∼ 377 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Gene ID (Entrez):
4921

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.