89-018-838

presenilin 1, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-018-838-Each-of-1 In Stock ₹ 29,603.76

89-018-838 - Each of 1

₹ 29,603.76

In Stock

Quantity

1

Base Price: ₹ 29,603.76

GST (18%): ₹ 5,328.677

Total Price: ₹ 34,932.437

Antigen

presenilin 1

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant PSEN1.

Gene

PSEN1

Gene Alias

AD3/FAD/PS1/S182

Host Species

Mouse

Quantity

50 μL

Research Discipline

Apoptosis

Gene ID (Entrez)

5663

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

BC011729

Gene Symbols

PSEN1

Immunogen

PSEN1 (AAH11729, 280 a.a. ∼ 379 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Serum

Description

  • Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP)
  • These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains)
  • Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP
  • Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes
  • Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined
  • [provided by RefSeq] Sequence: PALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGL

Compare Similar Items

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Img

Abnova Corporation

89-018-838

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Antigen:
presenilin 1

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant PSEN1.

Gene:
PSEN1

Gene Alias:
AD3/FAD/PS1/S182

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
Apoptosis

Gene ID (Entrez):
5663

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
BC011729

Gene Symbols:
PSEN1

Immunogen:
PSEN1 (AAH11729, 280 a.a. ∼ 379 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Img

Abnova Corporation

89-018-840

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Antigen:
sucrase-isomaltase (alpha-glucosidase)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant SI.

Gene:
SI

Gene Alias:
MGC131621/MGC131622

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
__

Gene ID (Entrez):
6476

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_001041

Gene Symbols:
SI

Immunogen:
SI (NP_001032, 1728 a.a. ∼ 1826 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Img

Abnova Corporation

89-018-843

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Antigen:
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant SRD5A2.

Gene:
SRD5A2

Gene Alias:
MGC138457

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
__

Gene ID (Entrez):
6716

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_000348

Gene Symbols:
SRD5A2

Immunogen:
SRD5A2 (NP_000339.2, 28 a.a. ∼ 65 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum

Img

Abnova Corporation

89-018-844

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Antigen:
thyroglobulin

Classification:
Polyclonal

Description:
Mouse polyclonal antibody raised against a partial recombinant TG.

Gene:
TG

Gene Alias:
AITD3/TGN

Host Species:
Mouse

Quantity:
50 μL

Research Discipline:
__

Gene ID (Entrez):
7038

Content And Storage:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Formulation:
50% glycerol

Gene Accession No.:
NM_003235

Gene Symbols:
TG

Immunogen:
TG (NP_003226, 2671 a.a. ∼ 2768 a.a) partial recombinant protein with GST tag.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Serum